Recent advances in nanomaterial‐assisted combinational sonodynamic cancer therapy

S Liang, X Deng, P Ma, Z Cheng, J Lin - Advanced Materials, 2020 - Wiley Online Library
Ultrasound (US)‐triggered sonodynamic therapy (SDT), as a promising noninvasive
therapeutic modality, has received ever‐increasing attention in recent years. Its specialized …

Precise nanomedicine for intelligent therapy of cancer

H Chen, Z Gu, H An, C Chen, J Chen, R Cui… - Science China …, 2018 - Springer
Precise nanomedicine has been extensively explored for efficient cancer imaging and
targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and …

[HTML][HTML] Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapy

W Zhang, X Hu, Q Shen, D Xing - Nature communications, 2019 - nature.com
Cancer cells exhibit slightly elevated levels of reactive oxygen species (ROS) compared with
normal cells, and approximately 90% of intracellular ROS is produced in mitochondria. In …

Polyprodrug nanomedicines: an emerging paradigm for cancer therapy

K Yang, Z Yang, G Yu, Z Nie, R Wang… - Advanced …, 2022 - Wiley Online Library
Nanomedicines have the potential to provide advanced therapeutic strategies in combating
tumors. Polymer‐prodrug‐based nanomedicines are particularly attractive in cancer …

Enhanced antitumor efficacy by a cascade of reactive oxygen species generation and drug release

S Wang, G Yu, Z Wang, O Jacobson, LS Lin… - Angewandte …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) can be used not only as a therapeutic agent for
chemodynamic therapy (CDT), but also as a stimulus to activate release of antitumor drugs …

Temperature-responsive multilayer films of micelle-based composites for controlled release of a third-generation EGFR inhibitor

L Xu, H Wang, Z Chu, L Cai, H Shi, C Zhu… - ACS Applied Polymer …, 2020 - ACS Publications
Lung cancer is a complicated long-term disease, which is extremely difficult to cure. A
traditional single drug delivery system cannot achieve desired long-term controlled release …

Carrier-free nanomedicines for cancer treatment

LH Liu, XZ Zhang - Progress in Materials Science, 2022 - Elsevier
The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Tumor‐specific drug release and reactive oxygen species generation for cancer chemo/chemodynamic combination therapy

S Wang, Z Wang, G Yu, Z Zhou, O Jacobson… - Advanced …, 2019 - Wiley Online Library
The combination of chemotherapeutic drugs and reactive oxygen species (ROS) is a
promising strategy to achieve improved anticancer effect. Herein, a nanomedicine …

Research progress on self-assembled nanodrug delivery systems

L Qiao, H Yang, S Gao, L Li, X Fu, Q Wei - Journal of materials …, 2022 - pubs.rsc.org
In recent years, nanodrug delivery systems have attracted increasing attention due to their
advantages, such as high drug loading, low toxicity and side effects, improved …

Polymersomes for therapeutic delivery of protein and nucleic acid macromolecules: from design to therapeutic applications

S Iqbal, M Blenner, A Alexander-Bryant… - …, 2020 - ACS Publications
Macromolecule-based therapeutic agents, particularly proteins, antigens, monoclonal
antibodies, transcription factors, nucleic acids, and gene editing enzymes, have the potential …