Oxidative stress (OS), defined as disturbances in the pro-/antioxidant balance, is harmful to
cells due to the excessive generation of highly reactive oxygen (ROS) and nitrogen (RNS) …

Myeloperoxidase (MPO) is a member of the superfamily of heme peroxidases that is mainly
expressed in neutrophils and monocytes. MPO-derived reactive species play a key role in …

Significance: The release of myeloperoxidase (MPO) by activated leukocytes is critical in
innate immune responses. MPO produces hypochlorous acid (HOCl) and other strong …

The heme peroxidase family generates a battery of oxidants both for synthetic purposes, and
in the innate immune defence against pathogens. Myeloperoxidase (MPO) is the most …

Neutrophils are predominant immune cells that protect the human body against infections by
deploying sophisticated antimicrobial strategies including phagocytosis of bacteria and …

Myeloperoxidase (MPO) belongs to the family of heme-containing peroxidases, produced
mostly from polymorphonuclear neutrophils. The active enzyme (150 kDa) is the product of …

Aims Systemic levels of trimethylamine N-oxide (TMAO), a pro-atherogenic and pro-
thrombotic metabolite produced from gut microbiota metabolism of dietary trimethylamine …

Inflammation is one of the common events in the majority of acute as well as chronic
debilitating diseases and represent a chief cause of morbidity in today's era of modern …

Over the past millennia, life expectancy has drastically increased. While a mere 25 years
during Bronze and Iron ages, life expectancy in many European countries and in Japan is …

ESC Guidelines 3002 recommendations. To implement the guidelines, condensed pocket
guidelines versions, summary slides, booklets with essential messages, and an electronic …