Advances in data‐independent acquisition mass spectrometry towards comprehensive digital proteome landscape

RB Kitata, JC Yang, YJ Chen - Mass spectrometry reviews, 2023 - Wiley Online Library
The data‐independent acquisition mass spectrometry (DIA‐MS) has rapidly evolved as a
powerful alternative for highly reproducible proteome profiling with a unique strength of …

[HTML][HTML] Exosomal therapy—A new frontier in regenerative medicine

S Muthu, A Bapat, R Jain, N Jeyaraman… - Stem Cell …, 2021 - ncbi.nlm.nih.gov
The recent advances in translational and nanomedicine have paved the way for developing
the targeted drug delivery system at a greater pace among global researchers. On par with …

[HTML][HTML] Global trend in exosome isolation and application: an update concept in management of diseases

M Omrani, H Beyrampour-Basmenj… - Molecular and Cellular …, 2024 - Springer
Extracellular vesicles (EVs) secreted by various cells offer great potential for use in the
diagnosis and treatment of disease. EVs are heterogeneous membranous vesicles …

[HTML][HTML] A novel machine learning algorithm selects proteome signature to specifically identify cancer exosomes

B Li, FG Kugeratski, R Kalluri - Elife, 2024 - elifesciences.org
Non-invasive early cancer diagnosis remains challenging due to the low sensitivity and
specificity of current diagnostic approaches. Exosomes are membrane-bound nanovesicles …

[HTML][HTML] Proteomics, personalized medicine and cancer

M Su, Z Zhang, L Zhou, C Han, C Huang, EC Nice - Cancers, 2021 - mdpi.com
Simple Summary Cancer, a major public health issue worldwide, is the second most
common cause of death. Initiatives such as the Human Genome Project (HGP) and Human …

Lactobacillus gasseri and Gardnerella vaginalis produce extracellular vesicles that contribute to the function of the vaginal microbiome and modulate host …

A Artuyants, J Hong, P Dauros‐Singorenko… - Molecular …, 2023 - Wiley Online Library
Trichomonas vaginalis is an extracellular protozoan parasite of the human urogenital tract,
responsible for a prevalent sexually transmitted infection. Trichomoniasis is accompanied by …

[HTML][HTML] Blood-based biomarkers for glioma in the context of gliomagenesis: a systematic review

H Ali, R Harting, R de Vries, M Ali, T Wurdinger… - Frontiers in …, 2021 - frontiersin.org
Background Gliomas are the most common and aggressive tumors of the central nervous
system. A robust and widely used blood-based biomarker for glioma has not yet been …

[HTML][HTML] Glioblastoma biomarkers in urinary extracellular vesicles reveal the potential for a 'liquid gold'biopsy

SM Hallal, Á Tűzesi, LA Sida, E Xian, D Madani… - British Journal of …, 2024 - nature.com
Background Biomarkers that reflect glioblastoma tumour activity and treatment response are
urgently needed to help guide clinical management, particularly for recurrent disease. As the …

Advances in mass spectrometry for clinical analysis: Data acquisition, interpretation and information integration

H Zhang, Z Ouyang, W Zhang - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Bioinformatics has played an important role in analyzing chemical information acquired
using mass spectrometry (MS) for large numbers of biological samples. Here we review the …

Chaperonins in cancer: Expression, function, and migration in extracellular vesicles

AJL Macario, EC de Macario - Seminars in Cancer Biology, 2022 - Elsevier
The chaperonins CCT and Hsp60 are molecular chaperones, members of the chaperone
system (CS). Chaperones are cytoprotective but if abnormal in quantity or quality they may …