Application of mesenchymal stem cells for therapeutic agent delivery in anti-tumor treatment

DS Chulpanova, KV Kitaeva, LG Tazetdinova… - Frontiers in …, 2018 - frontiersin.org
Mesenchymal stem cells (MSCs) are non-hematopoietic progenitor cells, which can be
isolated from different types of tissues including bone marrow, adipose tissue, tooth pulp …

Chemotherapy-induced metastasis: mechanisms and translational opportunities

GS Karagiannis, JS Condeelis, MH Oktay - Clinical & experimental …, 2018 - Springer
Tumors often overcome the cytotoxic effects of chemotherapy through either acquired or
environment-mediated drug resistance. In addition, signals from the microenvironment …

Recent advances on drug-loaded mesenchymal stem cells with anti-neoplastic agents for targeted treatment of cancer

A Babajani, P Soltani, E Jamshidi, MH Farjoo… - … in bioengineering and …, 2020 - frontiersin.org
Mesenchymal stem cells (MSCs), as an undifferentiated group of adult multipotent cells,
have remarkable antitumor features that bring them up as a novel choice to treat cancers …

Mesenchymal stem cells, exosomes and exosome-mimics as smart drug carriers for targeted cancer therapy

H Liu, S Deng, L Han, Y Ren, J Gu, L He, T Liu… - Colloids and Surfaces B …, 2022 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stem cells with the capacity to differentiate
into several cell types under appropriate conditions. They also possess remarkable …

Enhancement of the therapeutic capacity of mesenchymal stem cells by genetic modification: a systematic review

JA Pawitan, TA Bui, W Mubarok… - Frontiers in Cell and …, 2020 - frontiersin.org
Background The therapeutic capacity of mesenchymal stem cells (also known as
mesenchymal stromal cells/MSCs) depends on their ability to respond to the need of the …

Nanotechnology and bioengineering approaches to improve the potency of mesenchymal stem cell as an off‐the‐shelf versatile tumor delivery vehicle

M Taheri, HA Tehrani, S Dehghani… - Medicinal Research …, 2024 - Wiley Online Library
Targeting actionable mutations in oncogene‐driven cancers and the evolution of immuno‐
oncology are the two prominent revolutions that have influenced cancer treatment …

Therapeutic potential and protection enhancement of mesenchymal stem cell against cisplatin-induced nephrotoxicity using hyaluronic acid-chitosan nanoparticles as …

SA Altalhi, AA Shati, MY Alfaifi, FA Al-Salmi… - International Journal of …, 2023 - Elsevier
A newly synthesized nanoplatform of hyaluronic acid and chitosan nanoparticles (HA/CNPs)
was applied to improve the therapeutic efficacy and protection of bone marrow …

The current understanding of mesenchymal stem cells as potential attenuators of chemotherapy‐induced toxicity

A Rühle, PE Huber, R Saffrich… - … journal of cancer, 2018 - Wiley Online Library
Chemotherapeutic agents are part of the standard treatment algorithms for many
malignancies; however, their application and dosage are limited by their toxic effects to …

Human mesenchymal stem cells lose their functional properties after paclitaxel treatment

F Münz, R Lopez Perez, T Trinh, S Sisombath… - Scientific reports, 2018 - nature.com
Mesenchymal stem cells (MSCs) are an integral part of the bone marrow niche and aid in
the protection, regeneration and proliferation of hematopoietic stem cells after exposure to …

Mesenchymal stem cells are sensitive to bleomycin treatment

NH Nicolay, A Rühle, RL Perez, T Trinh, S Sisombath… - Scientific reports, 2016 - nature.com
Mesenchymal stem cells (MSCs) have been shown to attenuate pulmonary damage induced
by bleomycin-based anticancer treatments, but the influence of bleomycin on the stem cells …