Microneedles for painless transdermal immunotherapeutic applications

H Amani, MA Shahbazi, C D'Amico, F Fontana… - Journal of Controlled …, 2021 - Elsevier
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …

Microneedles: a new generation vaccine delivery system

I Menon, P Bagwe, KB Gomes, L Bajaj, R Gala… - Micromachines, 2021 - mdpi.com
Transdermal vaccination route using biodegradable microneedles is a rapidly progressing
field of research and applications. The fear of painful needles is one of the primary reasons …

[HTML][HTML] Trends in drug-and vaccine-based dissolvable microneedle materials and methods of fabrication

LE Moore, S Vucen, AC Moore - European Journal of Pharmaceutics and …, 2022 - Elsevier
Microneedle patches, also called microarray patches (MAP), are an emerging technology for
delivery and sampling of drugs, vaccines and other materials. This review focuses on the …

Minoxidil-loaded hyaluronic acid dissolving microneedles to alleviate hair loss in an alopecia animal model

MJ Kim, KY Seong, JS Jeong, SY Kim, S Lee, SY Yang… - Acta Biomaterialia, 2022 - Elsevier
Alopecia is defined as hair loss in a part of the head due to various causes, such as drugs,
stress and autoimmune disorders. Various therapeutic agents have been suggested …

Application of alginate-based hydrogels in hemostasis

Y Xie, P Gao, F He, C Zhang - Gels, 2022 - mdpi.com
Hemorrhage, as a common trauma injury and clinical postoperative complication, may
cause serious damage to the body, especially for patients with huge blood loss and …

Polysaccharide-based transdermal drug delivery

J Li, H Xiang, Q Zhang, X Miao - Pharmaceuticals, 2022 - mdpi.com
Materials derived from natural plants and animals have great potential for transdermal drug
delivery. Polysaccharides are widely derived from marine, herbal, and microbial sources …

Exploiting unique features of microneedles to modulate immunity

C Edwards, SA Shah, T Gebhardt… - Advanced …, 2023 - Wiley Online Library
Microneedle arrays (MNAs) are small patches containing hundreds of short projections that
deliver signals directly to dermal layers without causing pain. These technologies are of …

Marine polymeric microneedles for transdermal drug delivery

T Moniz, SAC Lima, S Reis - Carbohydrate Polymers, 2021 - Elsevier
Transdermal drug delivery is considered one of the most attractive routes for administration
of pharmaceutic and cosmetic active ingredients due to the numerous advantages …

Progress in microneedle array patch (MAP) for vaccine delivery

TT Nguyen, Y Oh, Y Kim, Y Shin, SK Baek… - Human Vaccines & …, 2021 - Taylor & Francis
ABSTRACT A microneedle array patch (MAP) has been developed as a new delivery
system for vaccines. Preclinical and clinical trials with a vaccine MAP showed improved …

Recent advances in polymer microneedles for drug transdermal delivery: Design strategies and applications

R Wang, G Jiang, UE Aharodnikau… - Macromolecular …, 2022 - Wiley Online Library
In recent years, transdermal drug delivery based on microneedles (MNs) technology has
received extensive attention, which offers a safer and painless alternative to hypodermic …