Liquid biopsies in cancer diagnosis, monitoring, and prognosis

G De Rubis, SR Krishnan, M Bebawy - Trends in pharmacological sciences, 2019 - cell.com
Liquid biopsies, comprising the noninvasive analysis of circulating tumor-derived material
(the 'tumor circulome'), represent an innovative tool in precision oncology to overcome …

[HTML][HTML] Liquid biopsy for advanced non-small cell lung cancer (NSCLC): a statement paper from the IASLC

C Rolfo, PC Mack, GV Scagliotti, P Baas… - Journal of thoracic …, 2018 - Elsevier
The isolation and analysis of circulating cell-free tumor DNA in plasma is a powerful tool with
considerable potential to improve clinical outcomes across multiple cancer types, including …

Liquid biopsy and non-small cell lung cancer: are we looking at the tip of the iceberg?

L Bonanno, A Dal Maso, A Pavan, E Zulato… - British journal of …, 2022 - nature.com
The possibility to analyse the tumour genetic material shed in the blood is undoubtedly one
of the main achievements of translational research in the latest years. In the modern clinical …

Liquid biopsies, novel approaches and future directions

A Armakolas, M Kotsari, J Koskinas - Cancers, 2023 - mdpi.com
Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …

[HTML][HTML] Targets, pitfalls and reference materials for liquid biopsy tests in cancer diagnostics

E Geeurickx, A Hendrix - Molecular aspects of medicine, 2020 - Elsevier
Assessment of cell free DNA (cfDNA) and RNA (cfRNA), circulating tumor cells (CTC) and
extracellular vesicles (EV) in blood or other bodily fluids can enable early cancer detection …

Prognostic Value and Relation with Adjuvant Treatment Duration of ctDNA in Stage III Colon Cancer: a Post Hoc Analysis of the PRODIGE-GERCOR IDEA-France …

J Taieb, V Taly, J Henriques, C Bourreau, L Mineur… - Clinical Cancer …, 2021 - AACR
Abstract Purpose: Circulating tumor DNA (ctDNA) has been suggested as a major
prognostic factor in resected stage-III colon cancer. We analyzed ctDNA of patients …

Evaluation of commercial kits for purification of circulating free DNA

RJ Diefenbach, JH Lee, RF Kefford, H Rizos - Cancer genetics, 2018 - Elsevier
Abstract Analysis of liquid biopsies and the identification of non-invasive biomarkers for the
diagnosis and prognosis of solid tumors has grown exponentially over the last few years …

New perspectives on the importance of cell-free DNA biology

AJ Bronkhorst, V Ungerer, A Oberhofer, S Gabriel… - Diagnostics, 2022 - mdpi.com
Body fluids are constantly replenished with a population of genetically diverse cell-free DNA
(cfDNA) fragments, representing a vast reservoir of information reflecting real-time changes …

The liquid biopsy for lung cancer: state of the art, limitations and future developments

D Di Capua, D Bracken-Clarke, K Ronan, AM Baird… - Cancers, 2021 - mdpi.com
Simple Summary During the development and progression of lung tumors, processes such
as necrosis and vascular invasion shed tumor cells or cellular components into various fluid …

Harmonizing cell-free DNA collection and processing practices through evidence-based guidance

SR Greytak, KB Engel, S Parpart-Li, M Murtaza… - Clinical Cancer …, 2020 - AACR
Circulating cell-free DNA (cfDNA) is rapidly transitioning from discovery research to an
important tool in clinical decision making. However, the lack of harmonization of preanalytic …