Neurotransmitters: The critical modulators regulating gut–brain axis
R Mittal, LH Debs, AP Patel, D Nguyen… - Journal of cellular …, 2017 - Wiley Online Library
Neurotransmitters, including catecholamines and serotonin, play a crucial role in
maintaining homeostasis in the human body. Studies on these neurotransmitters mainly …
maintaining homeostasis in the human body. Studies on these neurotransmitters mainly …
Second-generation antipsychotics induce cardiotoxicity by disrupting spliceosome signaling: Implications from proteomic and transcriptomic analyses
J Wang, X Li, Z Liu, X Lin, F Zhong, S Li, X Tang… - Pharmacological …, 2021 - Elsevier
Second-generation antipsychotics (SGAs) are first-line drugs that are prescribed for mental
disorders in clinic. Severe cardiotoxicity has been widely reported and thus limits their …
disorders in clinic. Severe cardiotoxicity has been widely reported and thus limits their …
Lebetin 2, a snake venom-derived natriuretic peptide, attenuates acute myocardial ischemic injury through the modulation of mitochondrial permeability transition pore …
B Tourki, P Matéo, J Morand, M Elayeb… - PLoS …, 2016 - journals.plos.org
Cardiac ischemia is one of the leading causes of death worldwide. It is now well established
that natriuretic peptides can attenuate the development of irreversible ischemic injury during …
that natriuretic peptides can attenuate the development of irreversible ischemic injury during …
Lebetin 2, a snake venom-derived b-type natriuretic peptide, provides immediate and prolonged protection against myocardial ischemia-reperfusion injury via …
B Tourki, A Dumesnil, E Belaidi, S Ghrir… - Toxins, 2019 - mdpi.com
Myocardial infarction (MI) followed by left ventricular (LV) remodeling is the most frequent
cause of heart failure. Lebetin 2 (L2), a snake venom-derived natriuretic peptide, exerts …
cause of heart failure. Lebetin 2 (L2), a snake venom-derived natriuretic peptide, exerts …
Triiodo-L-thyronine (T3) downregulates Npr1 gene (coding for natriuretic peptide receptor-A) transcription in H9c2 cells: involvement of β-AR-ROS signaling
G Nagaraj, E Vellaichamy - Endocrine, 2024 - Springer
Introduction Natriuretic peptide receptor-A (NPR-A) signaling system is considered as an
intrinsic productive mechanism of the heart that opposes abnormal cardiac remodeling and …
intrinsic productive mechanism of the heart that opposes abnormal cardiac remodeling and …
[HTML][HTML] The discovery of hidden guanylate cyclases (GCs) in the Homo sapiens proteome
Recent discoveries have established functional guanylate cyclase (GC) catalytic centers
with low activity within kinase domains in plants. These crypto GCs generate guanosine 3', 5' …
with low activity within kinase domains in plants. These crypto GCs generate guanosine 3', 5' …
Valporic acid enhances the Atrial Natriuretic Peptide (ANP) mediated anti-hypertrophic activity by modulating the Npr1 gene transcription in H9c2 cells in vitro
S Manivasagam, T Velusamy, B Sowndharajan… - European Journal of …, 2017 - Elsevier
The present study was aimed to determine whether stimulating Npr1 gene activity using
Valporic acid (VA), a small short chain fatty acid molecule can enhance ANP mediated anti …
Valporic acid (VA), a small short chain fatty acid molecule can enhance ANP mediated anti …
Suppression of Npr1, not Npr2 gene function induces hypertrophic growth in H9c2 cells in vitro
S Manivasagam, E Vellaichamy - Biochemical and biophysical research …, 2017 - Elsevier
Npr1 gene (coding for NPR-A) and Npr2 gene (coding for NPR-B) are identified as intrinsic
anti-hypertrophic genes that opposes abnormal cardiac remodeling. However, the functional …
anti-hypertrophic genes that opposes abnormal cardiac remodeling. However, the functional …
Enhanced Activation of Atrial Natriuretic Peptide (ANP) and Natriuretic Peptide Receptor-A (NPRA) in Chronic Cigarette Smoke-Induced Lung Inflammation in …
AA Babu, E Vellaichamy - International Journal of Peptide Research and …, 2021 - Springer
We sought to determine the circulatory level of atrial natriuretic peptide (ANP) and its
receptor (Natriuretic peptide receptor-A) on different (7, 15, 30 and 45) days of cigarette …
receptor (Natriuretic peptide receptor-A) on different (7, 15, 30 and 45) days of cigarette …
Avaliação dos efeitos de derivados aminoguanidínicos na hipertrofia cardíaca induzida em ratos
CA Silva Júnior - 2018 - repositorio.ufal.br
Estimativas divulgadas pela Organização Mundial da Saúde (WHO–World Health
Organization) indicam que em 2030 as doenças cardiovasculares serão responsáveis por …
Organization) indicam que em 2030 as doenças cardiovasculares serão responsáveis por …