Thromboembolic and hemorrhagic complications continue to remain frequent complications
that significantly impact the morbidity and mortality of patients implanted with mechanical …

Heparinases are enzymes that selectively cleave heparin and heparan sulfate chains, via
cleavage of the glycosidic linkage between hexosamines and uronic acids, producing …

Viscoelastic tests, specifically thromboelastography and rotational thromboelastometry, are
increasingly being used in the management of postoperative bleeding in surgical intensive …

Introduction To determine if anti-Xa testing is associated with improved outcomes for
patients< 19-years-old on ECMO. Methods We evaluated the clinical benefit of anti-Xa …

Background Patients undergoing major surgery frequently experience major uncontrolled
bleeding. The aim of this systematic review and meta‐analysis was to evaluate the clinical …

Objectives: Using a rabbit in vivo joint injury model, the primary objective of the study was to
determine if a relationship exists between earlier time to initiation of ketotifen fumarate (KF) …

Abstract Coronavirus disease 2019 (COVID-19)-associated coagulopathy is unusual, poorly
defined and is linked with significant hypercoagulability and microthrombotic and …

In the intensive care unit (ICU), continuous intravenous infusion of unfractionated heparin
(UFH) is a relatively common form of anticoagulation therapy. 1, 2 Monitoring the …

Abstract The TEG® Hemostasis Analyzer measures the viscoelastic properties of blood in
order to provide a comprehensive real-time analysis of hemostasis, from initial fibrin fiber …

Background As both APTT and APTT-based coagulation method cannot distinguish heparin
effect from intrinsic coagulation factor deficiency, we implemented thromboelastography …