Phosphatases and kinases maintain an equilibrium of dephosphorylated and
phosphorylated proteins, respectively, that are required for critical cellular functions …

Papaver somniferum and Cannabis sativa are ancient medicinal plants that contain
secondary metabolites with multiple pharmacological properties, such as benzylisoquinoline …

An increased number antibiotic-resistant bacteria have emerged with the rise in antibiotic
use worldwide. As such, there has been a growing interest in investigating novel antibiotics …

Reversible phosphorylation by protein kinases and phosphatases plays a central role in
regulating cellular processes. However, knowledge of the functions of protein phosphatase …

Context Sanguinarine (SAG) is the most abundant constituent of Macleaya cordata (Willd.)
R. Br.(Popaceae). SAG has shown antimammary and colorectal metastatic effects in mice in …

Porcine reproductive and respiratory syndrome virus (PRRSV), the etiological agent of
PRRS, is prevalent worldwide, causing substantial and immense economic losses to the …

Alkaloids are nitrogen-containing compounds, biosynthesized by both marine and terrestrial
organisms, often with strong biological properties. They are among the largest classes of …

Collective total syntheses of 10 benzo [c] phenanthridines were achieved on the basis of the
construction of rings C and B through sequential transition metal-catalyzed reactions and …

California poppy or golden poppy (Eschscholzia californica) is the iconic state flower of
California, with native ranges from Northern California to Southwestern Mexico. It grows well …

Sanguinarine (1) is a natural product with significant pharmacological effects. However, the
application of sanguinarine has been limited due to its toxic side effects and a lack of clarity …