A clinical approach to diagnosis of autoimmune encephalitis

F Graus, MJ Titulaer, R Balu, S Benseler… - The lancet …, 2016 - thelancet.com
Encephalitis is a severe inflammatory disorder of the brain with many possible causes and a
complex differential diagnosis. Advances in autoimmune encephalitis research in the past …

The immunopathogenesis of narcolepsy type 1

RS Liblau, D Latorre, BR Kornum… - Nature Reviews …, 2024 - nature.com
Abstract Narcolepsy type 1 (NT1) is a chronic sleep disorder resulting from the loss of a
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …

Updated diagnostic criteria for paraneoplastic neurologic syndromes

F Graus, A Vogrig, S Muñiz-Castrillo… - Neurology …, 2021 - AAN Enterprises
Objective The contemporary diagnosis of paraneoplastic neurologic syndromes (PNSs)
requires an increasing understanding of their clinical, immunologic, and oncologic …

Acute symptomatic seizures secondary to autoimmune encephalitis and autoimmune‐associated epilepsy: conceptual definitions

C Steriade, J Britton, RC Dale, A Gadoth, SR Irani… - …, 2020 - Wiley Online Library
Seizures are a well‐recognized and often prominent manifestation of autoimmune
encephalitic syndromes. Progress in detection of pathogenic neural autoantibodies has led …

Paraneoplastic neurological syndromes in the era of immune-checkpoint inhibitors

F Graus, J Dalmau - Nature Reviews Clinical Oncology, 2019 - nature.com
Paraneoplastic neurological syndromes (PNSs) comprise a group of disorders that can
affect any part of the nervous system in patients with cancer and frequently result from …

Autoimmune encephalopathies

F Leypoldt, T Armangue… - Annals of the New York …, 2015 - Wiley Online Library
Over the past 10 years, the continual discovery of novel forms of encephalitis associated
with antibodies to cell‐surface or synaptic proteins has changed the paradigms for …

Autoimmune encephalitis: pathophysiology and imaging review of an overlooked diagnosis

BP Kelley, SC Patel, HL Marin… - American Journal …, 2017 - Am Soc Neuroradiology
Autoimmune encephalitis is a relatively new category of immune-mediated disease
involving the central nervous system that demonstrates a widely variable spectrum of clinical …

Kelch-like protein 11 antibodies in seminoma-associated paraneoplastic encephalitis

C Mandel-Brehm, D Dubey, TJ Kryzer… - … England Journal of …, 2019 - Mass Medical Soc
A 37-year-old man with a history of seminoma presented with vertigo, ataxia, and diplopia.
An autoantibody specific for kelch-like protein 11 (KLHL11) was identified with the use of …

The current role of MRI in differentiating multiple sclerosis from its imaging mimics

R Geraldes, O Ciccarelli, F Barkhof… - Nature Reviews …, 2018 - nature.com
MRI red flags proposed over a decade ago by the European Magnetic Resonance Network
in MS (MAGNIMS) have guided clinicians in the diagnosis of multiple sclerosis (MS) …

Neuronal autoantigens—pathogenesis, associated disorders and antibody testing

E Lancaster, J Dalmau - Nature Reviews Neurology, 2012 - nature.com
The discovery of disorders that are associated with antibodies to neuronal cell-surface
proteins has led to a paradigm shift in our understanding of CNS autoimmunity. These …