HIV-associated neurocognitive disorder—pathogenesis and prospects for treatment
In the past two decades, several advancements have improved the care of HIV-infected
individuals. Most importantly, the development and deployment of combination antiretroviral …
individuals. Most importantly, the development and deployment of combination antiretroviral …
HIV-1-associated neurocognitive disorder: epidemiology, pathogenesis, diagnosis, and treatment
C Eggers, G Arendt, K Hahn, IW Husstedt… - Journal of …, 2017 - Springer
The modern antiretroviral treatment of human immunodeficiency virus (HIV-1) infection has
considerably lowered the incidence of opportunistic infections. With the exception of the …
considerably lowered the incidence of opportunistic infections. With the exception of the …
HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors
Combination antiretroviral therapy (CART) has greatly reduced medical morbidity and
mortality with HIV infection, but high rates of HIV-associated neurocognitive disorders …
mortality with HIV infection, but high rates of HIV-associated neurocognitive disorders …
Controversies in HIV-associated neurocognitive disorders
S Nightingale, A Winston, S Letendre… - The Lancet …, 2014 - thelancet.com
Cross-sectional studies show that around half of individuals infected with HIV-1 have some
degree of cognitive impairment despite the use of antiretroviral drugs. However, prevalence …
degree of cognitive impairment despite the use of antiretroviral drugs. However, prevalence …
Pathways to neuronal injury and apoptosis in HIV-associated dementia
Abstract Human immunodeficiency virus-1 (HIV-1) can induce dementia with alarming
occurrence worldwide. The mechanism remains poorly understood, but discovery in brain of …
occurrence worldwide. The mechanism remains poorly understood, but discovery in brain of …
Human immunodeficiency virus‐associated neurocognitive disorders: mind the gap
JC McArthur, J Steiner, N Sacktor, A Nath - Annals of neurology, 2010 - Wiley Online Library
Human immunodeficiency virus (HIV)‐associated neurocognitive disorders (HANDs) remain
among the most common disorders in people infected with HIV, even in an era when potent …
among the most common disorders in people infected with HIV, even in an era when potent …
The prevalence and incidence of neurocognitive impairment in the HAART era
KR Robertson, M Smurzynski, TD Parsons, K Wu… - Aids, 2007 - journals.lww.com
Objectives: HAART suppresses HIV viral replication and restores immune function. The
effects of HAART on neurological disease are less well understood. The aim of this study …
effects of HAART on neurological disease are less well understood. The aim of this study …
Neurological complications of HIV infection
Cognitive disorders, vacuolar myelopathy, and sensory neuropathies associated with HIV
are the most common disorders in patients with HIV AIDS, and are the focus of this review …
are the most common disorders in patients with HIV AIDS, and are the focus of this review …
Impact of combination antiretroviral therapy on cerebrospinal fluid HIV RNA and neurocognitive performance
Objective: To determine whether antiretroviral regimens with good central nervous system
(CNS) penetration control HIV in cerebrospinal fluid (CSF) and improve cognition. Design …
(CNS) penetration control HIV in cerebrospinal fluid (CSF) and improve cognition. Design …
HIV dementia: an evolving disease
JC McArthur - Journal of neuroimmunology, 2004 - Elsevier
Several advances have led to improvements in the care and prognosis of HIV+ individuals.
The first is an understanding of the direct relationship between HIV replication and …
The first is an understanding of the direct relationship between HIV replication and …