Bile acids are important hydroxylated steroids that are synthesized in the liver from
cholesterol for intestinal absorption of lipids and other fatty-nutrient. They also display …

Despite advances in preoperative evaluation and postoperative care, intervention,
especially surgery, for relief of obstructive jaundice still carries high morbidity and mortality …

Gastroesophageal reflux is associated with adenocarcinoma in Barrett's esophagus, but the
incidence of this tumor is rising, despite widespread use of acid-suppressing medications …

Nuclear factor kappa B (NF-κB) is a redox-associated transcription factor that is involved in
the activation of survival pathways. We have previously shown that deoxycholate (DOC) …

Bile acids (BAs) are synthesized in the liver and secreted into the intestine. In the lumen,
enteric bacteria metabolize BAs from conjugated, primary forms into more toxic …

Total parenteral nutrition (TPN) is essential for patients with impaired gut function but leads
to parenteral nutrition-associated liver disease (PNALD). TPN disrupts the normal …

Background and aims Mechanisms of the progression from Barrett's oesophagus to
oesophageal adenocarcinoma (OA) are not fully understood. Bile acids may have an …

BACKGROUND & AIMS: It is not clear why only a minority of patients with gastroesophageal
reflux disease (GERD) develop Barrett's esophagus. We hypothesized that differences …

A new bacterial strain, designated 452T, was isolated from the rhizosphere soil of the
mangrove Avicennia marina in China. As determined, its cell wall peptidoglycan contained ll …

Bile acids (BAs) have been implicated in regulation of intestinal epithelial signaling and
function. This study aimed to investigate the effects of hyodeoxycholic acid (HDCA) on …