Mu opioid receptor activation mediates (S)-ketamine reinforcement in rats: implications for abuse liability

MR Levinstein, ML Carlton, T Di Ianni, EN Ventriglia… - Biological …, 2023 - Elsevier
Background (S)-ketamine is an NMDA receptor antagonist, but it also binds to and activates
mu opioid receptors (MORs) and kappa opioid receptors in vitro. However, the extent to …

Exploring the role of mu opioid receptors in the therapeutic potential and abuse liability of (S)-ketamine

MR Levinstein, M Michaelides - … publication of the American College of …, 2024 - nature.com
(R, S)-ketamine is a racemic mixture made up of (S)-ketamine and (R)-ketamine
enantiomers in equal proportion.(R, S)-ketamine has shown promise as a rapid-acting …

[HTML][HTML] Optimization of a Nucleophilic Two-Step Radiosynthesis of 6-O-(2-[18F]fluoroethyl)-6-O-desmethyl-diprenorphine ([18F]FE-DPN) for PET Imaging of Brain …

E Németh, B Gyuricza, V Forgács, P Cumming… - International journal of …, 2023 - mdpi.com
We have established a method for nucleophilic one-pot, two-step radiosynthesis of the
popular opioid receptor radioligand 6-O-(2-[18F] fluoroethyl)-6-O-desmethyl-diprenorphine …

Effect of miR-146a polymorphism on lipoic acid therapy in patients with T2DM peripheral polyneuropthy

Y Li, Y Jia - Cellular and Molecular Biology, 2023 - cellmolbiol.org
For investigating the impact of miR-146a rs2910164 polymorphism on the therapeutic
efficacy of lipoic acid therapy in patients with type 2 diabetes mellitus (T2DM) peripheral …

Endogenous opiates and behavior: 2023

RJ Bodnar - Peptides, 2024 - Elsevier
This paper is the forty-sixth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …