Development is a complex process regulated both by genetic and epigenetic and
environmental clues. Recently, long non-coding RNAs (lncRNAs) have emerged as key …

The human genome is pervasively transcribed, producing a majority of short and long
noncoding RNAs (lncRNAs) that can influence cellular programs through a variety of …

Neurodevelopmental diseases (NDDs), such as autism spectrum disorders, epilepsy, and
schizophrenia, are characterized by diverse facets of neurological and psychiatric …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

N 6-methyladenosine (m 6 A) is the most abundant modification in eukaryotic cells, and it
regulates RNA transcription, processing, splicing, degradation, and translation. Long non …

Objective Cognitive impairment is a common neurological disease of which NLRP3-related
neuroinflammation has been demonstrated to be an essential mediator. Previous studies …

Recent advances in RNA sequencing technologies helped to uncover the existence of tens
of thousands of long non-coding RNAs (lncRNAs) that arise from the dark matter of the …

The discovery of the microbiota-gut-brain axis has revolutionized our understanding of
systemic influences on brain function and may lead to novel therapeutic approaches to …

Mitochondrial function and integrity are vital for the maintenance of cellular homeostasis,
particularly in high-energy demanding cells. Cardiomyocytes have a large number of …

RNA metabolism is central to cellular physiopathology. Almost all the molecular pathways
underpinning biological processes are affected by the events governing the RNA life cycle …