Bacillus sp. is one of the most distinctive gram-positive bacteria, able to grow efficiently
using cheap carbon sources and secrete a variety of useful substances, which are widely …

Micronutrient deficiency is a form of malnutrition responsible for different metabolic diseases,
widely shared among developing low-and middle-income African countries. While …

The production efficiency of microbial cell factories is sometimes limited by the lack of
effective methods to regulate multiple targets in a coordinated manner. Here taking the …

Riboflavin (RF) is a vitamin that only exists in plants and microorganisms and must be
procured externally by humans. On the other hand, there are two major allergic factors in …

L-methionine is an essential amino acid with versatile applications in food, feed, cosmetics
and pharmaceuticals. At present, the production of L-methionine mainly relies on chemical …

Pyrimidine nucleosides, as intermediate materials of significant commercial value, find
extensive applications in the pharmaceutical industry. However, the current production of …

Riboflavin (vitamin B2) is one of the essential vitamins that the human body needs to
maintain normal metabolism. Its biosynthesis has become one of the successful models for …

Mutagenesis driving genetic diversity is vital for understanding and engineering biological
systems. However, the lack of effective methods to generate in-situ mutagenesis in multiple …

Levulinic acid, a hydrolysis product of lignocellulose, can be metabolized into important
compounds in the field of medicine and pesticides by engineered strains of Saccharomyces …

Improving the biocompatibility and water dispersibility of hydroxyapatite (HAP) is an effective
way to expand its application in biomedicine. Here, we present a nanosystem (HAP-β-CD …