Genome-wide association studies (GWAS) have revealed thousands of genetic loci that
underpin the complex biology of many human traits. However, the strength of GWAS–the …

Cellular life depends on a complex web of functional associations between biomolecules.
Among these associations, protein–protein interactions are particularly important due to their …

Many real-world datasets can be naturally represented as graphs, spanning a wide range of
domains. However, the increasing complexity and size of graph datasets present significant …

Graph data widely exist in many high-impact applications. Inspired by the success of deep
learning in grid-structured data, graph neural network models have been proposed to learn …

Improved bioassays have significantly increased the rate of identifying new protein-protein
interactions (PPIs), and the number of detected human PPIs has greatly exceeded early …

Gene regulatory elements, including promoters, enhancers, silencers, etc., control
transcriptional programs in a spatiotemporal manner. Though these elements are known to …

Motivation Quantitative detection of histone modifications has emerged in the recent years
as a major means for understanding such biological processes as chromosome packaging …

Elucidating the role of 3D architecture of DNA in gene regulation is crucial for understanding
cell differentiation, tissue homeostasis and disease development. Among various chromatin …

Over the last decade, genome-wide association studies (GWAS) have discovered thousands
of genetic variants underlying complex human diseases and agriculturally important traits …

Abstract “Psychobiotics” are a novel class of probiotics that are beneficial to the health and
functional efficiency of our brain and psychology. The main hold on command in ill …