The question of how genomic information is expressed to determine phenotypes is of central
importance for basic and translational life science research and has been studied by …

Mass spectrometry (MS) based proteomics have achieved a near-complete proteome
coverage in humans and in several other organisms, producing a wealth of information …

The data-independent acquisition (DIA) approach has recently been introduced as a novel
mass spectrometric method that promises to combine the high content aspect of shotgun …

To further integrate mass spectrometry (MS)-based proteomics into biomedical research and
especially into clinical settings, high throughput and robustness are essential requirements …

Mass spectrometry is the method of choice for deep and reliable exploration of the (human)
proteome. Targeted mass spectrometry reliably detects and quantifies pre-determined sets …

The degree and the origins of quantitative variability of most human plasma proteins are
largely unknown. Because the twin study design provides a natural opportunity to estimate …

Targeted proteomics technique has emerged as a powerful protein quantification tool in
systems biology, biomedical research, and increasing for clinical applications. The most …

The myriad of peptides presented at the cell surface by class I and class II major
histocompatibility complex (MHC) molecules are referred to as the immunopeptidome and …

In the era of quantitative proteomics, where mass spectrometry plays a pivotal role, in
particular associated with the use of data‐independent acquisition, it is time to perform an …

In medicine, there is an urgent need for protein biomarkers in a range of applications that
includes diagnostics, disease stratification, and therapeutic decisions. One of the main …