Hybrid epithelial/mesenchymal phenotypes promote metastasis and therapy resistance across carcinomas

MK Jolly, JA Somarelli, M Sheth, A Biddle… - Pharmacology & …, 2019 - Elsevier
Cancer metastasis and therapy resistance are the major unsolved clinical challenges, and
account for nearly all cancer-related deaths. Both metastasis and therapy resistance are …

MiRNA-155–5p inhibits epithelium-to-mesenchymal transition (EMT) by targeting GSK-3β during radiation-induced pulmonary fibrosis

D Wang, Z Liu, Z Yan, X Liang, X Liu, Y Liu… - Archives of Biochemistry …, 2021 - Elsevier
Radiation-induced pulmonary fibrosis (RIPF) is a major lung complication in using
radiotherapy to treat thoracic diseases. MicroRNAs (miRNAs) are reported to be the …

Ribosomal protein L22-like1 (RPL22L1) mediates sorafenib sensitivity via ERK in hepatocellular carcinoma

D Zhang, Y Zhou, Y Ma, P Jiang, H Lv, S Liu, Y Mu… - Cell Death …, 2022 - nature.com
Precision medicine in hepatocellular carcinoma (HCC) relies on validated biomarkers that
help subgroup patients for targeted treatment. Here, we identified a novel candidate …

Status of cancer research in India

P Sarma, P Sharma, R Singh, A Mishra, H Kumar… - 2018 - insajournal.in
Burden of cancer in India is increasing day by day. Projected number of new cancer cases in
2016 is 1,219,649. This brings with it the need for research to investigate different India …

mTORC1 Restricts Hepatitis C Virus Replication Through ULK1-mediated Suppression of miR-122 and Facilitates Post-replication Events

MK Johri, HV Lashkari, D Vedagiri, D Gupta… - bioRxiv, 2018 - biorxiv.org
Mechanistic target of rapamycin (mTOR) is an important kinase that assimilates several
upstream signals including viral infection and facilitates appropriate response by the cell …