Background: Alzheimer's disease (AD) and epilepsy represent two complex neurological
disorders with distinct clinical manifestations, yet recent research has highlighted their …

Network hyperexcitability (NH) is an important feature of the pathophysiology of Alzheimer's
disease. Functional connectivity (FC) of brain networks has been proposed as a potential …

(1) Background: Alzheimer's disease (AD), an age-progressive neurodegenerative disease
that affects cognitive function, causes changes in the functional connectivity of the default …

Given continued failure of BACE1 inhibitor programs at symptomatic and prodromal stages
of Alzheimer's disease (AD), clinical trials need to target the earlier preclinical stage …

Background Alterations in functional connectivity have been demonstrated in Alzheimer's
disease (AD), an age-progressive neurodegenerative disorder that affects cognitive function; …

The excitation‐inhibition imbalance manifesting as epileptic activities in Alzheimer's disease
is gaining more and more attention, and several potentially involved cellular and molecular …

2-arachidonoylglycerol (2-AG) is the most abundant endocannabinoid (EC), acting as a full
agonist at both CB1 and CB2 cannabinoid receptors. It is synthesized on demand in …

Due to shared hippocampal dysfunction, patients with Alzheimer's dementia and late-onset
epilepsy (LOE) report memory decline. Multiple studies have described the epidemiological …

While epilepsy incidence peaks in older adults (1, 2), the association between epilepsy and
Alzheimer's disease (AD) extends beyond the increased risk of AD with age. Epilepsy and …

Alzheimer's disease (AD) is a neurodegenerative disorder affecting nearly one in nine older
adults in the US. This number is expected to grow exponentially, thereby increasing stress …