Emerging and re-emerging coronaviruses in pigs

Q Wang, AN Vlasova, SP Kenney, LJ Saif - Current opinion in virology, 2019 - Elsevier
Highlights•Three coronaviruses are emerging/reemerging in pigs.•The three porcine
coronaviruses may have originated from other species.•The clinical signs and pathogenesis …

Coronavirus spike protein and tropism changes

RJG Hulswit, CAM De Haan, BJ Bosch - Advances in virus research, 2016 - Elsevier
Coronaviruses (CoVs) have a remarkable potential to change tropism. This is particularly
illustrated over the last 15 years by the emergence of two zoonotic CoVs, the severe acute …

[HTML][HTML] An update on feline infectious peritonitis: virology and immunopathogenesis

NC Pedersen - The Veterinary Journal, 2014 - Elsevier
Feline infectious peritonitis (FIP) continues to be one of the most researched infectious
diseases of cats. The relatively high mortality of FIP, especially for younger cats from …

Emergence of pathogenic coronaviruses in cats by homologous recombination between feline and canine coronaviruses

Y Terada, N Matsui, K Noguchi, R Kuwata, H Shimoda… - PloS one, 2014 - journals.plos.org
Type II feline coronavirus (FCoV) emerged via double recombination between type I FCoV
and type II canine coronavirus (CCoV). In this study, two type I FCoVs, three type II FCoVs …

Deletion of a 197-amino-acid region in the N-terminal domain of spike protein attenuates porcine epidemic diarrhea virus in piglets

Y Hou, CM Lin, M Yokoyama, BL Yount… - Journal of …, 2017 - Am Soc Microbiol
We previously isolated a porcine epidemic diarrhea virus (PEDV) strain, PC177, by blind
serial passaging of the intestinal contents of a diarrheic piglet in Vero cell culture. Compared …

Experimental feline enteric coronavirus infection reveals an aberrant infection pattern and shedding of mutants with impaired infectivity in enterocyte cultures

LMB Desmarets, BL Vermeulen, S Theuns… - Scientific reports, 2016 - nature.com
Feline infectious peritonitis (FIP) results from mutations in the viral genome during a
common feline enteric coronavirus (FECV) infection. Since many virological and …

Therapeutic effect of an anti-human-TNF-alpha antibody and itraconazole on feline infectious peritonitis

T Doki, M Toda, N Hasegawa, T Hohdatsu… - Archives of Virology, 2020 - Springer
Feline infectious peritonitis (FIP) is a fatal disease in wild and domestic cat species.
Although several drugs are expected to be useful as treatments for FIP, no drugs are …

Establishment of full-length cDNA clones and an efficient oral infection model for feline coronavirus in cats

G Wang, G Hu, R Liang, J Shi, X Qiu, Y Yang… - Journal of …, 2021 - Am Soc Microbiol
Feline infectious peritonitis virus (FIPV) is the etiologic agent of feline infectious peritonitis
(FIP) and causes fatal disease in cats of almost all ages. Currently, there are no clinically …

An updated review on betacoronavirus viral entry inhibitors: learning from past discoveries to advance COVID-19 drug discovery

DA Sabbah, R Hajjo, SK Bardaweel… - Current Topics in …, 2021 - ingentaconnect.com
Even after one year of its first outbreak reported in China, the coronavirus disease 2019
(COVID-19) pandemic is still sweeping the World, causing serious infections and claiming …

In vivo antiviral effects of U18666A against type I feline infectious peritonitis virus

T Doki, T Tarusawa, T Hohdatsu, T Takano - Pathogens, 2020 - mdpi.com
Background: The cationic amphiphilic drug U18666A inhibits the proliferation of type I FIPV
in vitro. In this study, we evaluated the in vivo antiviral effects of U18666A by administering it …