The formation of new blood vessels, called angiogenesis, is an essential pathophysiological
process in which several families of regulators have been implicated. Among these, vascular …

The timely resolution of wound healing is critical for restoring the skin as a protective barrier.
The switch from a proinflammatory to a reparative microenvironment must be tightly …

Background Geographic atrophy is an advanced form of dry age-related macular
degeneration that can lead to irreversible vision loss and high burden of disease. We aimed …

Several CRISPR-Cas9 orthologues have been used for genome editing. Here, we present
the smallest Cas9 orthologue characterized to date, derived from Campylobacter jejuni …

Myopia is a highly frequent ocular disorder worldwide and pathologic myopia is the 4th most
common cause of irreversible blindness in developed countries. Pathologic myopia is …

Abstract Background/Objectives To assess the safety and efficacy of avacincaptad pegol
(ACP), a C5 inhibitor, for geographic atrophy (GA) secondary to age-related macular …

The possible interconnection between the eye and central nervous system (CNS) has been
a topic of discussion for several years just based on fact that the eye is properly considered …

There are two major types of ocular neovascularization that affect the retina, retinal
neovascularization (NV) and subretinal or choroidal NV. Retinal NV occurs in a group of …

As the age of the population increases in many nations, age‐related degenerative diseases
pose significant socioeconomic challenges. One of the key degenerative diseases that …

Age-related macular degeneration (AMD) is a common irreversible ocular disease
characterized by vision impairment among older people. Many risk factors are related to …