Recent advances in preclinical modeling of urinary tract infections (UTIs) have enabled the
identification of key facets of the host response that influence pathogen clearance and tissue …

Inflammation and fibrosis are two pathological features of chronic kidney disease (CKD).
Transforming growth factor-β (TGF-β) has been long considered as a key mediator of renal …

Oxidative stress is an imbalance between pro-and antioxidants that adversely influences the
organism in various mechanisms and on many levels. Oxidative damage occurring …

Ischemia/reperfusion injury (I/R) is one of the leading causes of acute kidney injury (AKI) that
typically occurs in renal surgeries. However, renal I/R still currently lacks effective …

Urinary tract infections (UTIs) are among the most common bacterial infections seen in
clinical practice. The ascent of UTI-causing pathogens to the kidneys results in …

Diabetic nephropathy (DN), a sterile inflammatory disease, is a serious complication of
diabetes mellitus. However, recent evidence indicates that pyroptosis, a new term for pro …

Innovative solutions are needed for the treatment of bacterial infections, and a range of
antibacterial molecules have been explored as alternatives to antibiotics. A different …

Abstract Aims Ischemia-reperfusion (I/R)-induced acute kidney injury (AKI) shows high
mortality. Hydrogen sulfide (H 2 S) is essential for regulating kidney function. This study …

Background/Aims: Ischemia/reperfusion injury (IRI) plays a crucial role in renal
transplantation and can cause renal failure associated with pyroptosis, a pro-inflammatory …

Rhodiola is an ancient wild plant that grows in rock areas in high-altitude mountains with a
widespread habitat in Asia, Europe, and America. From empirical belief to research studies …