Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …

Ketone bodies play significant roles in organismal energy homeostasis, serving as oxidative
fuels, modulators of redox potential, lipogenic precursors, and signals, primarily during …

The ketone bodies beta-hydroxybutyrate and acetoacetate are hepatically produced
metabolites catabolized in extrahepatic organs. Ketone bodies are a critical cardiac fuel and …

The pandemic caused by the new coronavirus has caused shock waves in many countries,
producing a global health crisis worldwide. Lack of knowledge of the biological mechanisms …

Very‐low‐carbohydrate diet triggers the endogenous production of ketone bodies as
alternative energy substrates. There are as yet unproven assumptions that ketone bodies …

Obesity, diabetes mellitus (mostly type 2), and COVID-19 show mutual interactions because
they are not only risk factors for both acute and chronic COVID-19 manifestations, but also …

Human SARS‐CoV‐2 infection is characterized by a high mortality rate due to some patients
developing a large innate immune response associated with a cytokine storm and acute …

Ketone bodies are small compounds derived from fatty acids that behave as an alternative
mitochondrial energy source when insulin levels are low, such as during fasting or …

Nonalcoholic fatty liver disease (NAFLD) is a global health concern with no approved drugs.
High-protein dietary intervention is currently the most effective treatment. However, its …

The decades-long dietary experiment embodied in the Dietary Guidelines for Americans
(DGA) focused on limiting fat, especially saturated fat, and higher carbohydrate intake has …