Parkinson disease (PD) is the second most common neurodegenerative disorder, affecting>
1% of the population≥ 65 years of age and with a prevalence set to double by 2030. In …

Dementia is a frequent problem encountered in advanced stages of Parkinson disease (PD).
In recent years, research has focused on the pre-dementia stages of cognitive impairment in …

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Abstract Background Dementia with Lewy bodies (DLB) and Parkinson's disease dementia
(PDD), which share many clinical, neurochemical, and morphological features, have been …

Patients with Parkinson's disease have a number of specific visual disturbances. These
include changes in colour vision and contrast sensitivity and difficulties with complex visual …

Many aspects of cognition and behaviour are regulated by noradrenergic projections to the
forebrain originating from the locus coeruleus, acting through alpha and beta …

Dementia is increasingly being recognized in cases of Parkinson's disease (PD); such cases
are termed PD dementia (PDD). The spread of fibrillar α-synuclein (α-syn) pathology from …

In the long-term, with progression of the illness, Parkinson's disease dementia affects up to
90% of patients with Parkinson's disease. With increasing life expectancy in western …

Non motor symptoms (NMS) represent a significant burden in Parkinson's disease (PD) with
numerous studies highlighting the importance of NMS both in “pre-motor” phase of PD as …

Background Prognosis in Parkinson's disease (PD) remains poorly understood due to a lack
of unbiased data on the natural history of treated PD. The CamPaIGN study has been the …