Malaria: biology and disease
Malaria has been a major global health problem of humans through history and is a leading
cause of death and disease across many tropical and subtropical countries. Over the last …
cause of death and disease across many tropical and subtropical countries. Over the last …
Tools and strategies for malaria control and elimination: what do we need to achieve a grand convergence in malaria?
J Hemingway, R Shretta, TNC Wells, D Bell… - PLoS …, 2016 - journals.plos.org
Progress made in malaria control during the past decade has prompted increasing global
dialogue on malaria elimination and eradication. The product development pipeline for …
dialogue on malaria elimination and eradication. The product development pipeline for …
Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization
Virus-like particles (VLPs) are non-infectious self-assembling nanoparticles, useful in
medicine and nanotechnology. Their repetitive molecularly-defined architecture is attractive …
medicine and nanotechnology. Their repetitive molecularly-defined architecture is attractive …
Engineering a rugged nanoscaffold to enhance plug-and-display vaccination
Nanoscale organization is crucial to stimulating an immune response. Using self-
assembling proteins as multimerization platforms provides a safe and immunogenic system …
assembling proteins as multimerization platforms provides a safe and immunogenic system …
Antibodies against Plasmodium falciparum malaria at the molecular level
JP Julien, H Wardemann - Nature Reviews Immunology, 2019 - nature.com
Malaria is a vector-borne disease of global importance, with the vast majority of its life-
threatening cases caused by infection with Plasmodium falciparum parasites. Repeated …
threatening cases caused by infection with Plasmodium falciparum parasites. Repeated …
[HTML][HTML] Recent advances in recombinant protein-based malaria vaccines
SJ Draper, E Angov, T Horii, LH Miller, P Srinivasan… - Vaccine, 2015 - Elsevier
Plasmodium parasites are the causative agent of human malaria, and the development of a
highly effective vaccine against infection, disease and transmission remains a key priority. It …
highly effective vaccine against infection, disease and transmission remains a key priority. It …
Comparative Assessment of Transmission-Blocking Vaccine Candidates against Plasmodium falciparum
MC Kapulu, DF Da, K Miura, Y Li, AM Blagborough… - Scientific reports, 2015 - nature.com
Malaria transmission-blocking vaccines (TBVs) target the development of Plasmodium
parasites within the mosquito, with the aim of preventing malaria transmission from one …
parasites within the mosquito, with the aim of preventing malaria transmission from one …
A universal plug-and-display vaccine carrier based on HBsAg VLP to maximize effective antibody response
A Marini, Y Zhou, Y Li, IJ Taylor, DB Leneghan… - Frontiers in …, 2019 - frontiersin.org
Development of effective malaria vaccines requires delivery platforms to enhance the
immunogenicity and efficacy of the target antigens. This is particularly challenging for …
immunogenicity and efficacy of the target antigens. This is particularly challenging for …
[HTML][HTML] Malaria elimination and eradication
The world has made tremendous progress in the fight against malaria in the past 15 years.
According to the World Malaria Report, malaria case incidence was reduced by 41 percent …
According to the World Malaria Report, malaria case incidence was reduced by 41 percent …
Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology
Y Li, DB Leneghan, K Miura, D Nikolaeva, IJ Brian… - Scientific reports, 2016 - nature.com
Transmission-blocking vaccines (TBV) target the sexual-stages of the malaria parasite in the
mosquito midgut and are widely considered to be an essential tool for malaria elimination …
mosquito midgut and are widely considered to be an essential tool for malaria elimination …