Mechanistic pathways of sex differences in cardiovascular disease
V Regitz-Zagrosek, G Kararigas - Physiological reviews, 2017 - journals.physiology.org
Major differences between men and women exist in epidemiology, manifestation,
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …
Cardiac mitochondria and arrhythmias
DA Brown, B O'Rourke - Cardiovascular research, 2010 - academic.oup.com
Despite a high prevalence of sudden cardiac death throughout the world, the mechanisms
that lead to ventricular arrhythmias are not fully understood. Over the last 20 years, a …
that lead to ventricular arrhythmias are not fully understood. Over the last 20 years, a …
Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts
N Gaborit, A Varro, S Le Bouter, V Szuts… - Journal of molecular and …, 2010 - Elsevier
Gender-related differences in ventricular electrophysiology are known to be important
determinants of human arrhythmic risk, but the underlying molecular basis is poorly …
determinants of human arrhythmic risk, but the underlying molecular basis is poorly …
[HTML][HTML] Recent advances in understanding sex differences in cardiac repolarization
A number of gender differences exist in the human electrocardiogram (ECG): the P-wave
and PR intervals are slightly longer in men than in women, whilst women have higher …
and PR intervals are slightly longer in men than in women, whilst women have higher …
Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKα2 but not AMPKα1
K Sakamoto, E Zarrinpashneh… - American Journal …, 2006 - journals.physiology.org
Recent studies indicate that the LKB1 is a key regulator of the AMP-activated protein kinase
(AMPK), which plays a crucial role in protecting cardiac muscle from damage during …
(AMPK), which plays a crucial role in protecting cardiac muscle from damage during …
Gender differences in cardioprotection against ischemia/reperfusion injury in adult rat hearts: focus on Akt and protein kinase C signaling
Previous studies have reported the sex differences in heart susceptibility to
ischemia/reperfusion (I/R) injury, but the mechanisms are not understood. The present study …
ischemia/reperfusion (I/R) injury, but the mechanisms are not understood. The present study …
Susceptibility of the heart to ischaemia–reperfusion injury and exercise‐induced cardioprotection are sex‐dependent in the rat
DA Brown, JM Lynch, CJ Armstrong… - The Journal of …, 2005 - Wiley Online Library
The cardioprotective effects of short‐term exercise against myocardial ischaemia–
reperfusion injury in male and female rats were examined. We subjected male and female …
reperfusion injury in male and female rats were examined. We subjected male and female …
Exercise preconditioning of the myocardium
AN Kavazis - Sports medicine, 2009 - Springer
Diseases of the heart (eg myocardial ischaemia reperfusion injury) remain the major cause
of death in the industrialized world. Therefore, developing a pragmatic countermeasure to …
of death in the industrialized world. Therefore, developing a pragmatic countermeasure to …
Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat
This study was conducted to examine the role of myocardial ATP‐sensitive potassium
(KATP) channels in exercise‐induced protection from ischaemia–reperfusion (I–R) injury …
(KATP) channels in exercise‐induced protection from ischaemia–reperfusion (I–R) injury …
The Sulfonylurea Receptor, an Atypical ATP-Binding Cassette Protein, and Its Regulation of the KATP Channel
MA Burke, RK Mutharasan, H Ardehali - Circulation research, 2008 - Am Heart Assoc
ATP-binding cassette (ABC) proteins are highly conserved and widely expressed throughout
nature and found in all organisms, both prokaryotic and eukaryotic. They mediate myriad …
nature and found in all organisms, both prokaryotic and eukaryotic. They mediate myriad …