Bipolar disorder is a chronic, recurrent condition with the usual onset during adolescence or
early adulthood. In the Diagnostic and Statistical Manual of Mental Disorders 5th edition, it is …

Abstract Background Phosphodiesterases (PDEs) have been associated with psychiatric
disorders in observational studies; however, the causality of associations remains …

Mood stabilizers are a category of medications used in the management of mood disorders.
The mood stabilizing properties of lithium were first reported in 1949 by John Cade, and …

Delorazepam, a derivative of diazepam, is a psychotropic drug belonging to the
benzodiazepine class. Used as a nervous-system inhibitor, it treats anxiety, insomnia, and …

Schizophrenia (SCZ) is a polygenic, complex mental disorder of which a diagnosis is often
made based on psychiatric history and clinical observation with few available objectives and …

Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental
disorder. This study aimed to examine whether miRNA expression abundance in total white …

Based on our previous finding of a seven-miRNA (hsa-miR-34a, miR-449a, miR-564, miR-
432, miR-548d, miR-572 and miR-652) signature as a potential biomarker for schizophrenia …

White matter lesions due to cerebral hypoperfusion may be an important pathophysiology in
vascular dementia and stroke, although the inherent mechanisms remain to be fully …

Lithium (Li) remains the first line long-term treatment of bipolar disorders notwithstanding a
high inter-individual variability of response. Significant research effort has been undertaken …

Bipolar disorder (BD) is a complex and severe mental illness that causes significant
suffering to patients. In addition to the burden of depressive and manic symptoms, patients …