Animal models of acute renal failure

AP Singh, A Muthuraman, AS Jaggi, N Singh… - Pharmacological …, 2012 - Elsevier
The animal models are pivotal for understanding the characteristics of acute renal failure
(ARF) and development of effective therapy for its optimal management. Since the etiology …

Modes of Inhibition of α‐Amylase and α‐Glucosidase by Aqueous Extract of Morinda lucida Benth Leaf

MI Kazeem, JO Adamson… - BioMed research …, 2013 - Wiley Online Library
Diabetes mellitus is a metabolic disorder of glucose metabolism. The management of blood
glucose level is the hallmark in the treatment of this disease. This may be achieved through …

Hesperidin alleviates acetaminophen induced toxicity in Wistar rats by abrogation of oxidative stress, apoptosis and inflammation

ST Ahmad, W Arjumand, S Nafees, A Seth, N Ali… - Toxicology letters, 2012 - Elsevier
Acetaminophen (APAP) is a widely used analgesic and antipyretic drug, but at high dose it
leads to undesirable side effects, such as hepatotoxicity and nephrotoxicity. The present …

Medicinal plants for in vitro antiplasmodial activities: A systematic review of literature

MT Lemma, AM Ahmed, MT Elhady, HT Ngo… - Parasitology …, 2017 - Elsevier
The increasing resistance of malaria to drugs raise the need to new antimalarial agents.
Antiplasmodial herbs and their active compounds are the most promising source the new …

Protective effect of the aqueous leaf and seed extract of Phyllanthus amarus on gentamicin and acetaminophen-induced nephrotoxic rats

AA Adeneye, AS Benebo - Journal of ethnopharmacology, 2008 - Elsevier
AIM OF THE STUDY: In African traditional medicine, different parts of Phyllanthus amarus
Schum. and Thonn.(family: Euphorbiaceae) are highly valued for the treatment of array of …

Nephroprotective Effect of Herbal Extract Eurycoma longifolia on Paracetamol‐Induced Nephrotoxicity in Rats

SM Chinnappan, A George… - Evidence‐Based …, 2019 - Wiley Online Library
Paracetamol (PCM) is a well‐known drug widely used for its analgesic and antipyretic
properties. PCM is generally considered as safe but overdose of PCM can cause …

[HTML][HTML] Hepatoprotective activity of the extract of Homalium letestui stem against paracetamol-induced liver injury

JE Okokon, JO Simeon, EE Umoh - Avicenna journal of …, 2017 - ncbi.nlm.nih.gov
Objective: H omalium letestui Pellegr (Flacourtiaceae) has been traditionally used by the
Ibibios of Southern Nigeria to treat stomach ulcer, malaria and other inflammatory diseases …

[PDF][PDF] Therapeutic efficacy of Pimpinella tirupatiensis (Apiaceae) on acetaminophen induced nephrotoxicity and oxidative stress in male albino rats

S Palani, S Raja, RP Kumar, S Jayakumar… - Int J PharmTech Res, 2009 - Citeseer
Pimpinella tirupatiensis (Apiaceae) is a herbaceous medicinal plant used to treat cough,
stomach, liver problems, asthma, ulcer and tooth ache in India and other Asian countries …

Acetaminophen induced kidney failure in rats: a dose response study

S Roy, S Pradhan, K Das, A Mandal - 2015 - mcc-idr.l2c2academy.co.in
Acetaminophen is a commonly used analgesic and antipyretic drug, high doses of which
cause hepatic and renal injury. In development and progression of kidney disease research …

[HTML][HTML] Modulatory potentials of aqueous leaf and unripe fruit extracts of Carica papaya Linn.(Caricaceae) against carbon tetrachloride and acetaminophen-induced …

O Awodele, O Yemitan, PU Ise… - Journal of Intercultural …, 2016 - ncbi.nlm.nih.gov
Materials and Methods: Rats were administered CCl 4 (3 ml/kg in olive oil, ip) followed by
oral administration of CPL and CPF at 2, 6 and 10 h intervals. The ACM model proceeded …