Malaria in pregnancy: from placental infection to its abnormal development and damage

CLL Chua, SKM Khoo, JLE Ong… - Frontiers in …, 2021 - frontiersin.org
Malaria remains a global health burden with Plasmodium falciparum accounting for the
highest mortality and morbidity. Malaria in pregnancy can lead to the development of …

Escaping the enemy's bullets: an update on how malaria parasites evade host immune response

CA Ezema, IU Okagu, TPC Ezeorba - Parasitology research, 2023 - Springer
Malaria continues to cause untold hardship to inhabitants of malaria-endemic regions,
causing significant morbidity and mortality that severely impact global health and the …

Molecular mechanisms of hematological and biochemical alterations in malaria: a review

IU Okagu, RN Aguchem, CA Ezema… - Molecular and …, 2022 - Elsevier
Malaria is a dangerous disease that contributes to millions of hospital visits and hundreds of
thousands of deaths, especially in children residing in sub-Saharan Africa. Although several …

Potential benefits of lycopene consumption: Rationale for using it as an adjuvant treatment for malaria patients and in several diseases

ELP Varela, ARQ Gomes… - Nutrients, 2022 - mdpi.com
Malaria is a disease that affects thousands of people around the world every year. Its
pathogenesis is associated with the production of reactive oxygen and nitrogen species …

CD4 T cell–dependent and–independent roles for IFN-γ in blood-stage malaria

LL Drewry, LL Pewe, LS Hancox… - The Journal of …, 2023 - journals.aai.org
Production of IFN-γ by CD4 T cells is widely theorized to control Plasmodium parasite
burden during blood-stage malaria. Surprisingly, the specific and crucial mechanisms …

Plasmodium falciparum-infected erythrocyte co-culture with the monocyte cell line THP-1 does not trigger production of soluble factors reducing brain microvascular …

J Storm, G Camarda, MJ Haley, D Brough, KN Couper… - Plos one, 2023 - journals.plos.org
Monocytes contribute to the pro-inflammatory immune response during the blood stage of a
Plasmodium falciparum infection, but their precise role in malaria pathology is not clear …

Biophysical tools and concepts enable understanding of asexual blood stage malaria

V Introini, MA Govendir, JC Rayner, P Cicuta… - Frontiers in Cellular …, 2022 - frontiersin.org
Forces and mechanical properties of cells and tissues set constraints on biological functions,
and are key determinants of human physiology. Changes in cell mechanics may arise from …

Alterations in haematological indices of indomethacin-ulcerated rats treated with Persea americana seed and Bryophyllum pinnatum leaf ethyl acetate fraction

ES Asiwe, PC Ejiogu, UE Enenebeaku… - GSC Biological and …, 2024 - gsconlinepress.com
This study determined the alterations in haematological parameters of indomethacin-
ulcerated rats treated with P. americana seed (PAS) and B. pinnatum leaf (BPL) ethyl …

[HTML][HTML] Close encounters: pathogenic protists-host cell interactions

MC Vanrell, PS Romano - Phagocytosis-Main Key of Immune …, 2023 - intechopen.com
In this chapter, we summarize the highlights of the early events in the interaction of parasitic
protists and the host cell. Pathogenic protists are a group of eukaryotic organisms …

Cuscuta reflexa Possess Potent Inhibitory Activity Against Human Malaria Parasite: An In Vitro and In Vivo Study

SB Ojha, RK Sah, E Madan, R Bansal, S Roy… - Current …, 2023 - Springer
Drug resistance to practically all antimalarial drugs in use necessitate the development of
new chemotherapeutics against malaria. In this aspect, traditionally used plants with folklore …