The role of oxidative stress-mediated inflammation in the development of T2DM-induced diabetic nephropathy: possible preventive action of tannins and other …
G Sahakyan, A Vejux, N Sahakyan - Molecules, 2022 - mdpi.com
Diabetic nephropathy is manifested in more than 10% of people with diabetes. It is a
common cause of kidney failure and end-stage kidney disease. Understanding of …
common cause of kidney failure and end-stage kidney disease. Understanding of …
[HTML][HTML] Type 2 diabetes mellitus and neurodegenerative disorders: The mitochondrial connection
IR Baduini, JEC Vildosola, S Kavehmoghaddam… - Pharmacological …, 2024 - Elsevier
The incidence of type 2 diabetes mellitus (T2DM) has increased in our society in recent
decades as the population ages, and this trend is not expected to revert. This is the same for …
decades as the population ages, and this trend is not expected to revert. This is the same for …
Mitochondrial protein dysfunction in pathogenesis of neurological diseases
L Wang, Z Yang, X He, S Pu, C Yang, Q Wu… - Frontiers in Molecular …, 2022 - frontiersin.org
Mitochondria are essential organelles for neuronal function and cell survival. Besides the
well-known bioenergetics, additional mitochondrial roles in calcium signaling, lipid …
well-known bioenergetics, additional mitochondrial roles in calcium signaling, lipid …
Genetically encoded ATP biosensors for direct monitoring of cellular ATP dynamics
D White III, Q Yang - Cells, 2022 - mdpi.com
Adenosine 5′-triphosphate, or ATP, is the primary molecule for storing and transferring
energy in cells. ATP is mainly produced via oxidative phosphorylation in mitochondria, and …
energy in cells. ATP is mainly produced via oxidative phosphorylation in mitochondria, and …
COVID‐19 and neurodegeneration: The mitochondrial connection
CA Denaro, YI Haloush, SY Hsiao, JJ Orgera… - Aging …, 2022 - Wiley Online Library
There is still a significant lack of knowledge regarding many aspects of the etiopathology
and consequences of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …
and consequences of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …
The Proteome Profile of Olfactory Ecto-Mesenchymal Stem Cells-Derived from Patients with Familial Alzheimer's Disease Reveals New Insights for AD Study
LJ Rochín-Hernández, MA Jiménez-Acosta… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD), the most common neurodegenerative disease and the first cause
of dementia worldwide, has no effective treatment, and its pathological mechanisms are not …
of dementia worldwide, has no effective treatment, and its pathological mechanisms are not …
Mitochondrial inorganic polyphosphate is required to maintain proteostasis within the organelle
RT Da Costa, P Urquiza, MM Perez, YG Du… - Frontiers in Cell and …, 2024 - frontiersin.org
The existing literature points towards the presence of robust mitochondrial mechanisms
aimed at mitigating protein dyshomeostasis within the organelle. However, the precise …
aimed at mitigating protein dyshomeostasis within the organelle. However, the precise …
Enzymatic depletion of mitochondrial inorganic polyphosphate (polyP) increases the generation of reactive oxygen species (ROS) and the activity of the pentose …
Inorganic polyphosphate (polyP) is an ancient biopolymer that is well preserved throughout
evolution and present in all studied organisms. In mammals, it shows a high co-localization …
evolution and present in all studied organisms. In mammals, it shows a high co-localization …
Human prune regulates the metabolism of mammalian inorganic polyphosphate and bioenergetics
Inorganic polyphosphate (polyP) is an evolutionarily conserved and ubiquitous polymer that
is present in all studied organisms. PolyP consists of orthophosphates (Pi) linked together by …
is present in all studied organisms. PolyP consists of orthophosphates (Pi) linked together by …
Mitochondrial inorganic polyphosphate (polyP) is a potent regulator of mammalian bioenergetics in SH-SY5Y cells: a proteomics and metabolomics study
M Guitart-Mampel, P Urquiza… - Frontiers in Cell and …, 2022 - frontiersin.org
Inorganic polyphosphate (polyP) is an ancient, ubiquitous, and well-conserved polymer
which is present in all the studied organisms. It is formed by individual subunits of …
which is present in all the studied organisms. It is formed by individual subunits of …