Alcoholic beverage consumption and chronic diseases

Y Zhou, J Zheng, S Li, T Zhou, P Zhang… - International journal of …, 2016 - mdpi.com
Epidemiological and experimental studies have consistently linked alcoholic beverage
consumption with the development of several chronic disorders, such as cancer …

Systematic review: diet–gene interactions and the risk of colorectal cancer

V Andersen, R Holst, U Vogel - Alimentary pharmacology & …, 2013 - Wiley Online Library
Background Diet contributes significantly to colorectal cancer (CRC) aetiology and may be
potentially modifiable. Aim To review diet–gene interactions, aiming to further the …

Association between polymorphisms in glutathione peroxidase and selenoprotein P genes, glutathione peroxidase activity, HRT use and breast cancer risk

C Meplan, LO Dragsted, G Ravn-Haren, A Tjønneland… - PloS one, 2013 - journals.plos.org
Breast cancer (BC) is one of the most common cancers in women. Evidence suggests that
genetic variation in antioxidant enzymes could influence BC risk, but to date the relationship …

Genetic polymorphisms associated with psoriasis and development of psoriatic arthritis in patients with psoriasis

ND Loft, L Skov, MK Rasmussen, R Gniadecki… - PloS one, 2018 - journals.plos.org
Background Psoriasis (PsO) is a chronic inflammatory disease with predominantly
cutaneous manifestations. Approximately one third of patients with PsO develop psoriatic …

[HTML][HTML] Orthogonal assay and QSAR modelling of Tox21 PPARγ antagonist in vitro high-throughput screening assay

J Ardenkjær-Skinnerup, ACVE Nissen… - Environmental …, 2024 - Elsevier
Disruption of signalling mediated by the nuclear receptor peroxisome proliferator-activated
receptor gamma (PPARγ) is associated with risk of cancer, metabolic diseases, and …

Virtual screening of the multi-gene regulatory molecular mechanism of Si-Wu-tang against non-triple-negative breast cancer based on network pharmacology …

Z Zhang, J Liu, Y Liu, D Shi, Y He, P Zhao - Journal of ethnopharmacology, 2021 - Elsevier
Abstract Ethnopharmacological relevance Si-Wu-Tang (SWT), a prestigious herbal formula
from China, has been extensively used for centuries for female-related diseases. It has been …

Pathway-based discovery of genetic interactions in breast cancer

W Wang, ZZ Xu, M Costanzo, C Boone, CA Lange… - PLoS …, 2017 - journals.plos.org
Breast cancer is the second largest cause of cancer death among US women and the
leading cause of cancer death among women worldwide. Genome-wide association studies …

[HTML][HTML] PPARγ antagonists induce aromatase transcription in adipose tissue cultures

J Ardenkjær-Skinnerup, D Saar, PSS Petersen… - Biochemical …, 2024 - Elsevier
Aromatase is the rate-limiting enzyme in the biosynthesis of estrogens and a key risk factor
for hormone receptor-positive breast cancer. In postmenopausal women, estrogens …

Chemopreventive and anti-tumor potential of vitamin E in preclinical breast cancer studies: A systematic review

MPS de Sousa, IC Pereira, KGF de Oliveira… - Clinical Nutrition …, 2023 - Elsevier
Background Vitamin E has been investigated for its antitumor potential, including the ability
to change cancer gene pathways as well as promote antioxidant and pro-oxidant activity …

Alcohol consumption and breast tumor gene expression

J Wang, YJ Heng, AH Eliassen, RM Tamimi… - Breast Cancer …, 2017 - Springer
Background Alcohol consumption is an established risk factor for breast cancer and the
association generally appears stronger among estrogen receptor (ER)-positive tumors …