Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism
AJ Kroker, JB Bruning - PPAR research, 2015 - Wiley Online Library
PPARγ (peroxisome proliferator activated receptor γ) is a ligand activated transcription factor
of the nuclear receptor superfamily that controls the expression of a variety of genes …
of the nuclear receptor superfamily that controls the expression of a variety of genes …
Pharmacogenetics of type 2 diabetes mellitus, the route toward tailored medicine
GC Mannino, F Andreozzi… - … /metabolism research and …, 2019 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is a chronic disease that has reached the levels of a global
epidemic. In order to achieve optimal glucose control, it is often necessary to rely on …
epidemic. In order to achieve optimal glucose control, it is often necessary to rely on …
Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application
X Sun, W Yu, C Hu - BioMed research international, 2014 - Wiley Online Library
With rapidly increasing prevalence, diabetes has become one of the major causes of
mortality worldwide. According to the latest studies, genetic information makes substantial …
mortality worldwide. According to the latest studies, genetic information makes substantial …
Defined drug release from 3D-printed composite tablets consisting of drug-loaded polyvinylalcohol and a water-soluble or water-insoluble polymer filler
T Tagami, N Nagata, N Hayashi, E Ogawa… - International journal of …, 2018 - Elsevier
Abstract 3D-printed tablets are a promising new approach for personalized medicine. In this
study, we fabricated composite tablets consisting of two components, a drug and a filler, by …
study, we fabricated composite tablets consisting of two components, a drug and a filler, by …
miR-374a-5p: a new target for diagnosis and drug resistance therapy in gastric cancer
R Ji, X Zhang, H Gu, J Ma, X Wen, J Zhou… - … Therapy-Nucleic Acids, 2019 - cell.com
Chemoresistance is one of the causes associated with poor prognosis in gastric cancer.
MicroRNAs (miRNAs) are important regulators of chemoresistance. Exosome-mediated …
MicroRNAs (miRNAs) are important regulators of chemoresistance. Exosome-mediated …
The pharmacogenetics of type 2 diabetes: a systematic review
OBJECTIVE We performed a systematic review to identify which genetic variants predict
response to diabetes medications. RESEARCH DESIGN AND METHODS We performed a …
response to diabetes medications. RESEARCH DESIGN AND METHODS We performed a …
Precision medicine: the future in diabetes care?
AJ Scheen - Diabetes Research and Clinical Practice, 2016 - Elsevier
Personalized medicine aims at better targeting therapeutic intervention to the individual to
maximize benefit and minimize harm. Type 2 diabetes (T2D) is a heterogeneous disease …
maximize benefit and minimize harm. Type 2 diabetes (T2D) is a heterogeneous disease …
[PDF][PDF] Insulin resistance and metabolic dysfunction-associated steatotic liver disease (MASLD): pathways of action of hypoglycemic agents
A del Carmen Maldonado-Rojas… - Annals of …, 2024 - sochob.cl
Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by
overweight/obesity, and the presence of type 2 diabetes mellitus is the most important …
overweight/obesity, and the presence of type 2 diabetes mellitus is the most important …
The Genetics of Diabetes: What We Can Learn from Drosophila
Diabetes mellitus is a heterogeneous disease characterized by hyperglycemia due to
impaired insulin secretion and/or action. All diabetes types have a strong genetic …
impaired insulin secretion and/or action. All diabetes types have a strong genetic …
Diabetes-related neurological implications and pharmacogenomics
CA Rojas-Carranza, RH Bustos-Cruz… - Current …, 2018 - ingentaconnect.com
Diabetes mellitus (DM) is the most commonly occurring cause of neuropathy around the
world and is beginning to grow in countries where there is a risk of obesity. DM Type …
world and is beginning to grow in countries where there is a risk of obesity. DM Type …