CAR T-cell therapy in autoimmune diseases

G Schett, A Mackensen, D Mougiakakos - The Lancet, 2023 - thelancet.com
Despite the tremendous progress in the clinical management of autoimmune diseases,
many patients do not respond to the currently used treatments. Autoreactive B cells play a …

ANCA-associated vasculitis: an update

S Almaani, LA Fussner, S Brodsky, AS Meara… - Journal of clinical …, 2021 - mdpi.com
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) represents a group
of small vessel vasculitides characterized by granulomatous and neutrophilic tissue …

KDIGO 2021 clinical practice guideline for the management of glomerular diseases

BH Rovin, SG Adler, J Barratt, F Bridoux… - Kidney …, 2021 - kidney-international.org
Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

[HTML][HTML] EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update

B Hellmich, B Sanchez-Alamo, JH Schirmer… - Annals of the …, 2024 - ard.bmj.com
Background Since the publication of the EULAR recommendations for the management of
antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several …

Rituximab versus azathioprine for maintenance of remission for patients with ANCA-associated vasculitis and relapsing disease: an international randomised …

RM Smith, RB Jones, U Specks, S Bond… - Annals of the …, 2023 - ard.bmj.com
Objective Following induction of remission with rituximab in anti-neutrophil cytoplasmic
antibody-associated vasculitis (AAV) relapse rates are high, especially in patients with …

Effect of reduced-dose vs high-dose glucocorticoids added to rituximab on remission induction in ANCA-associated vasculitis: a randomized clinical trial

S Furuta, D Nakagomi, Y Kobayashi, M Hiraguri… - Jama, 2021 - jamanetwork.com
Importance The current standard induction therapy for antineutrophil cytoplasm antibody
(ANCA)–associated vasculitis is the combination of high-dose glucocorticoids and …

Immunopathogenesis of ANCA-associated vasculitis

A Kronbichler, KH Lee, S Denicolò, D Choi… - International journal of …, 2020 - mdpi.com
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is an autoimmune
disorder which affects small-and, to a lesser degree, medium-sized vessels. ANCA …

Genetics of ANCA-associated vasculitis: role in pathogenesis, classification and management

G Trivioli, A Marquez, D Martorana, M Tesi… - Nature Reviews …, 2022 - nature.com
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) comprises
granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and eosinophilic …

Advances in understanding of pathogenesis and treatment of immune-mediated kidney disease: A review

S Kant, A Kronbichler, P Sharma, D Geetha - American Journal of Kidney …, 2022 - Elsevier
There continues to be rapid advancement in our understanding of the pathogenesis of
immune-mediated kidney disease. This progress has culminated in the development of …

ANCA associated vasculitis subtypes: recent insights and future perspectives

K Austin, S Janagan, M Wells… - Journal of …, 2022 - Taylor & Francis
The ANCA associated vasculitides (AAVs) affect a range of internal organs including ear
nose and throat, respiratory tract, kidneys, skin and nervous system. They include …