Recent advances in gut microbiota-associated natural products: structures, bioactivities, and mechanisms

H Dai, J Han, T Wang, WB Yin, Y Chen, H Liu - Natural product reports, 2023 - pubs.rsc.org
Covering: 2014 to June 2022 The gut microbiota has attracted increasing attention from
researchers due to its critical role in regulating human physiology and pathophysiology …

A descriptive review of the action mechanisms of berberine, quercetin and silymarin on insulin resistance/hyperinsulinemia and cardiovascular prevention

P Bellavite, S Fazio, F Affuso - Molecules, 2023 - mdpi.com
Insulin resistance (IR) and the associated hyperinsulinemia are early pathophysiological
changes which, if not well treated, can lead to type 2 diabetes, endothelial dysfunction and …

Navigating the B vitamins: Dietary diversity, microbial synthesis, and human health

Y Yang, Y Ke, X Liu, Z Zhang, R Zhang, F Tian, L Zhi… - Cell Host & Microbe, 2024 - cell.com
B vitamins are intricately involved in various physiological processes vital for health. Their
significance is complicated by the heterogeneous landscape of B vitamin distribution in diets …

Modulating the gut microbiota is involved in the effect of low-molecular-weight Glycyrrhiza polysaccharide on immune function

W Song, Y Wang, G Li, S Xue, G Zhang, Y Dang… - Gut …, 2023 - Taylor & Francis
ABSTRACT Low molecular weight (6.5 kDa) Glycyrrhiza polysaccharide (GP) exhibits good
immunomodulatory activity, however, the mechanism underlying GP-mediated regulation of …

Bacteroides ovatus accelerates metformin-induced vitamin B12 deficiency in type 2 diabetes patients by accumulating cobalamin

M Chen, Y Shu, Q Li, Z Kang, T Liu, H Zhou… - npj Biofilms and …, 2023 - nature.com
Abstract Vitamin B12 (VB12) deficiency, which may lead to hematologic and neurologic
symptoms, has been associated with metformin use, but the underlying mechanism is …

Impact of Baizhu, Daqingye, and Hehuanhua extracts on the human gut microbiome

JMS Lemons, AB Narrowe, LS Liu, J Firrman… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction In traditional Chinese medicine, the rhizome of Atractylodes macrocephala
(Baizhu), the leaves of Isatis indigotica (Daqingye), and the flowers of Albizia julibrissin …

Supplementation of Silymarin alone or in combination with Salvianolic acids B and Puerarin regulates gut microbiota and its metabolism to improve high-fat diet …

X Wang, Y Jin, C Di, Y Zeng, Y Zhou, Y Chen, Z Pan… - Nutrients, 2024 - mdpi.com
Silymarin, salvianolic acids B, and puerarin were considered healthy food agents with
tremendous potential to ameliorate non-alcoholic fatty liver disease (NAFLD). However, the …

[HTML][HTML] Bacterial butyrate mediates the anti-atherosclerotic effect of silybin

HR Shen, ZY Wang, Z Shen, TT Liu, YD Guo… - Biomedicine & …, 2023 - Elsevier
Silybin (SIL) is a versatile bioactive compound used for improving liver damage and lipid
disorders and is also thought to be beneficial for atherosclerosis (AS). The goal of this study …

Gut microbiota metabolite tyramine ameliorates high-fat diet-induced insulin resistance via increased Ca2+ signaling

P Ma, Y Zhang, Y Yin, S Wang, S Chen, X Liang… - The EMBO …, 2024 - embopress.org
The gut microbiota and their metabolites are closely linked to obesity-related diseases, such
as type 2 diabetes, but their causal relationship and underlying mechanisms remain largely …

Mixture of Peanut Skin Extract, Geniposide, and Isoquercitrin Improves the Hepatic Lipid Accumulation of Mice via Modification of Gut Microbiota Homeostasis and the …

M Yi, OB Fasina, Y Li, L Xiang, J Qi - International Journal of Molecular …, 2023 - mdpi.com
Metabolic-dysfunction-associated steatotic liver disease (MASLD, formerly known as
NAFLD) is a global chronic liver disease, and no licensed drugs are currently available for …