Peroxisome proliferator-activated receptors (PPARs) belong to the family of ligand-activated
nuclear receptors. The PPAR family consists of three subtypes encoded by three separate …

Autophagy is an important homeostatic cellular process encompassing a number of
consecutive steps indispensable for degrading and recycling cytoplasmic materials …

Purpose To assess whether the presence of peripheral nonperfusion on ultrawide field
(UWF) fluorescein angiography (FA) is associated with diabetic retinopathy (DR) severity …

This study aims to explore the role of fatty acid binding protein 4 (FABP4) in diabetic
retinopathy (DR), and to elucidate the potential regulatory mechanism. We firstly developed …

Lipid signaling is dysregulated in many diseases with vascular pathology, including cancer,
diabetic retinopathy, retinopathy of prematurity, and age-related macular degeneration. We …

Importance Diabetic nephropathy and diabetic retinopathy share many similarities in
pathophysiological processes. Preclinical studies have shown that sodium-glucose …

To investigate how sodium-glucose co-transporter 2 inhibitors (SGLT2is) add-on therapy for
metformin affects diabetic retinopathy (DR) progression in patients with type 2 diabetes …

There has been an increase in the range of non-insulin anti-hyperglycaemic agents used to
treat type 2 diabetes. With the globally rising rates of type 2 diabetes and complications such …

Rationale: Omega3 long-chain polyunsaturated fatty acids (ω3-PUFAs) are powerful
modulators of angiogenesis. However, little is known about the mechanisms governing ω3 …

Abstract Ethnopharmacological relevance Fufang Xueshuantong (FXST) is a traditional
Chinese patent medicine composed of Panax notoginseng (Burkill) FH Chen (Araliaceae) …