Antiviral properties of flavonoids and delivery strategies
This review summarizes the latest advancements in phytochemicals as functional antiviral
agents. We focused on flavonoids, like apigenin, vitexin, quercetin, rutin and naringenin …
agents. We focused on flavonoids, like apigenin, vitexin, quercetin, rutin and naringenin …
Drug nanocrystals: in vivo performances
L Gao, G Liu, J Ma, X Wang, L Zhou, X Li - Journal of controlled release, 2012 - Elsevier
Over the past few decades, there has been a considerable research interest in drug
nanocrystal system as a pharmaceutical approach for poorly soluble drugs. At the beginning …
nanocrystal system as a pharmaceutical approach for poorly soluble drugs. At the beginning …
Cell-based drug delivery
Drug delivery has been greatly improved over the years by means of chemical and physical
agents that increase bioavailability, improve pharmacokinetic and reduce toxicities. At the …
agents that increase bioavailability, improve pharmacokinetic and reduce toxicities. At the …
Nanoparticle properties modulate their attachment and effect on carrier red blood cells
DC Pan, JW Myerson, JS Brenner, PN Patel… - Scientific Reports, 2018 - nature.com
Attachment of nanoparticles (NPs) to the surface of carrier red blood cells (RBCs) profoundly
alters their interactions with the host organism, decelerating NP clearance from the …
alters their interactions with the host organism, decelerating NP clearance from the …
The effect of polymeric nanoparticles on biocompatibility of carrier red blood cells
D Pan, O Vargas-Morales, B Zern, AC Anselmo… - PloS one, 2016 - journals.plos.org
Red blood cells (RBCs) can be used for vascular delivery of encapsulated or surface-bound
drugs and carriers. Coupling to RBC prolongs circulation of nanoparticles (NP, 200 nm …
drugs and carriers. Coupling to RBC prolongs circulation of nanoparticles (NP, 200 nm …
Application of advances in endocytosis and membrane trafficking to drug delivery
Multidisciplinary research efforts in the field of drug delivery have led to the development of
a variety of drug delivery systems (DDS) designed for site-specific delivery of diagnostic and …
a variety of drug delivery systems (DDS) designed for site-specific delivery of diagnostic and …
Erythrocyte-based drug delivery
The use of a physiological carrier to deliver therapeutics throughout the body to both
improve their efficacy while minimising inevitable adverse side effects, is an extremely …
improve their efficacy while minimising inevitable adverse side effects, is an extremely …
Red blood cells as an efficient in vitro model for evaluating the efficacy of metallic nanoparticles
Blood and the linings of blood vessels may be regarded as a fifth tissue type. The human
body contains 5× 10 9 red blood cells (RBCs) per ml, a total of 2.5× 10 13 cells in the 5 l of …
body contains 5× 10 9 red blood cells (RBCs) per ml, a total of 2.5× 10 13 cells in the 5 l of …
Optimization of magnetic nanoparticles for engineering erythrocytes as theranostic agents
LM Slavu, A Antonelli, ES Scarpa, P Abdalla… - Biomaterials …, 2023 - pubs.rsc.org
The application of superparamagnetic iron oxide nanoparticles (SPIONs) in drug delivery,
magnetic resonance imaging, cell tracking, and hyperthermia has been long exploited …
magnetic resonance imaging, cell tracking, and hyperthermia has been long exploited …
Development of long circulating magnetic particle imaging tracers: use of novel magnetic nanoparticles and entrapment into human erythrocytes
A Antonelli, P Szwargulski, ES Scarpa, F Thieben… - …, 2020 - Taylor & Francis
Aim: Magnetic particle imaging (MPI) is highly promising for biomedical applications, but
optimal tracers for MPI, namely superparamagnetic iron oxide-based contrast agents, are …
optimal tracers for MPI, namely superparamagnetic iron oxide-based contrast agents, are …