Optimized method for robust transcriptome profiling of minute tissues using laser capture microdissection and low-input RNA-Seq

S Farris, Y Wang, JM Ward, SM Dudek - Frontiers in Molecular …, 2017 - frontiersin.org
Obtaining high quality RNA from complex biological tissues, such as the brain, is needed for
establishing high-fidelity cell-type specific transcriptomes. Although combining genetic …

An optimised protocol harnessing laser capture microdissection for transcriptomic analysis on matched primary and metastatic colorectal tumours

CAJ Ong, QX Tan, HJ Lim, NB Shannon, WK Lim… - Scientific Reports, 2020 - nature.com
Generation of large amounts of genomic data is now feasible and cost-effective with
improvements in next generation sequencing (NGS) technology. Ribonucleic acid …

Laser capture microdissection for transcriptomic profiles in human skin biopsies

S Santoro, ID Lopez, R Lombardi, A Zauli… - BMC Molecular …, 2018 - Springer
Background The acquisition of reliable tissue-specific RNA sequencing data from human
skin biopsy represents a major advance in research. However, the complexity of the process …

Investigate non-invasive early-diagnostic and prognostic biomarkers of colorectal cancer using targeted RNA sequencing

W Xue - 2018 - theses.lib.polyu.edu.hk
This study aims to find circulating messenger RNA (mRNA) markers for early diagnoses of
colorectal adenoma and diagnoses and potential prognoses of colorectal cancer (CRC) …