Measures of population immunity can predict the dominant clade of influenza A (H3N2) and reveal age-associated differences in susceptibility and specificity
K Kim, S Gouma, MC Vieira, ME Weirick, SE Hensley… - medRxiv, 2023 - medrxiv.org
For antigenically variable pathogens such as influenza, strain fitness is partly determined by
the relative availability of hosts susceptible to infection with that strain compared to others …
the relative availability of hosts susceptible to infection with that strain compared to others …
A speed limit on serial strain replacement from original antigenic sin
Many pathogens evolve to escape immunity, yet it remains difficult to predict whether
immune pressure will lead to diversification, serial replacement of one variant by another, or …
immune pressure will lead to diversification, serial replacement of one variant by another, or …
[HTML][HTML] High-throughput sequencing-based neutralization assay reveals how repeated vaccinations impact titers to recent human H1N1 influenza strains
AN Loes, RAL Tarabi, J Huddleston, L Touyon… - bioRxiv, 2024 - ncbi.nlm.nih.gov
The high genetic diversity of influenza viruses means that traditional serological assays
have too low throughput to measure serum antibody neutralization titers against all relevant …
have too low throughput to measure serum antibody neutralization titers against all relevant …
[HTML][HTML] Concepts and methods for predicting viral evolution
M Meijers, D Ruchnewitz, J Eberhardt, M Karmakar… - ArXiv, 2024 - ncbi.nlm.nih.gov
The seasonal human influenza virus undergoes rapid evolution, leading to significant
changes in circulating viral strains from year to year. These changes are typically driven by …
changes in circulating viral strains from year to year. These changes are typically driven by …