As a result of recent advances, remarkable images revealing the distribution of complex
lipids in tissues are now generated by matrix-assisted laser desorption/ionization imaging …

Mass spectrometry is being used in many clinical research areas ranging from toxicology to
personalized medicine. Of all the mass spectrometry techniques, mass spectrometry …

Mass spectrometry imaging (MSI) has proven to be extremely useful for applications such as
the spatial analysis of peptides and proteins in biological tissue, the performance …

Alzheimer's disease (AD) is a progressive neurodegenerative disease that is characterized
by senile plaques, neurofibrillary tangles, synaptic disruption and neuronal loss. Several …

Nowadays, matrix-assisted laser desorption/ionization time of flight mass spectrometry
(MALDI-TOF MS) is routinely implemented as the reference method for the swift and …

Histopathological diagnoses have been done in the last century based on hematoxylin and
eosin staining. These methods were complemented by histochemistry, electron microscopy …

BACKGROUND: Disturbances in prefrontal cortex phospholipid and fatty acid composition
have been reported in patients with schizophrenia (SCZ), often as an incomplete lipid profile …

Mass spectrometry imaging is a powerful tool for directly determining the distribution of
proteins, peptides, lipids, neurotransmitters, metabolites and drugs in neural tissue sections …

Imaging mass spectrometry is an emerging technique of great potential for investigating the
chemical architecture in biological matrices. Although the potential for studying …

Alzheimer's disease (AD) is a progressive neurodegenerative disease affecting millions of
patients worldwide. Previous studies have demonstrated alterations in the lipid composition …