[HTML][HTML] Burden of community-acquired pneumonia and unmet clinical needs

J Ferreira-Coimbra, C Sarda, J Rello - Advances in therapy, 2020 - Springer
Community-acquired pneumonia (CAP) is the leading cause of death among infectious
diseases and an important health problem, having considerable implications for healthcare …

Management of pneumonia in critically ill patients

C Cillóniz, A Torres, MS Niederman - bmj, 2021 - bmj.com
Severe pneumonia is associated with high mortality (short and long term), as well as
pulmonary and extrapulmonary complications. Appropriate diagnosis and early initiation of …

[HTML][HTML] Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016

A Rhodes, LE Evans, W Alhazzani, MM Levy… - Intensive care …, 2017 - Springer
Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012

RP Dellinger, MM Levy, A Rhodes, D Annane… - Critical care …, 2013 - journals.lww.com
Objective: To provide an update to the “Surviving Sepsis Campaign Guidelines for
Management of Severe Sepsis and Septic Shock,” last published in 2008. Design: A …

Updates on community acquired pneumonia management in the ICU

GB Nair, MS Niederman - Pharmacology & therapeutics, 2021 - Elsevier
While the world is grappling with the consequences of a global pandemic related to SARS-
CoV-2 causing severe pneumonia, available evidence points to bacterial infection with …

[HTML][HTML] Host-directed therapies for infectious diseases: current status, recent progress, and future prospects

A Zumla, M Rao, RS Wallis, SHE Kaufmann… - The Lancet Infectious …, 2016 - thelancet.com
Despite extensive global efforts in the fight against killer infectious diseases, they still cause
one in four deaths worldwide and are important causes of long-term functional disability …

Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults

LA Mandell, RG Wunderink, A Anzueto… - Clinical infectious …, 2007 - academic.oup.com
Improving the care of adult patients with community-acquired pneumonia (CAP) has been
the focus of many different organizations, and several have developed guidelines for …

Mechanisms of action and clinical application of macrolides as immunomodulatory medications

S Kanoh, BK Rubin - Clinical microbiology reviews, 2010 - Am Soc Microbiol
Macrolides have diverse biological activities and an ability to modulate inflammation and
immunity in eukaryotes without affecting homeostatic immunity. These properties have led to …

Pathogenesis, treatment, and prevention of pneumococcal pneumonia

T van der Poll, SM Opal - The Lancet, 2009 - thelancet.com
Pneumococcus remains the most common cause of community-acquired pneumonia
worldwide. Streptococcus pneumoniae is well adapted to people, and is a frequent …

Severe community-acquired pneumonia

MS Niederman, A Torres - European Respiratory Review, 2022 - Eur Respiratory Soc
Severe community-acquired pneumonia is the most life-threatening form of community-
acquired pneumonia, characterised by intensive care unit admission and high morbidity and …