Roughly one quarter of all genes code for integral membrane proteins that are inserted into
the plasma membrane of prokaryotes or the endoplasmic reticulum membrane of …

The signal recognition particle (SRP) and its receptor compose a universally conserved and
essential cellular machinery that couples the synthesis of nascent proteins to their proper …

Introduction The continuous emergence and rapid spread of multidrug-resistant bacteria
have accelerated the demand for the discovery of alternative antibiotics. Natural plants …

Numerous membrane proteins form multisubunit protein complexes, which contain both
integral and peripheral subunits, in addition to prosthetic groups. Bacterial membrane …

Summary The YidC/Oxa1/Alb3 family of membrane proteins facilitates the insertion and
assembly of membrane proteins in bacteria, mitochondria, and chloroplasts. Here we …

The evolutionarily conserved YidC/Oxa1p/Alb3 family of proteins plays important roles in the
membrane biogenesis in bacteria, mitochondria, and chloroplasts. The members in this …

Protein insertion into the bacterial inner membrane is facilitated by SecYEG or YidC.
Although SecYEG most likely constitutes the major integration site, small membrane proteins …

The inner membrane proteome of the model organism Escherichia coli is composed of inner
membrane proteins, lipoproteins and peripherally attached soluble proteins. Our knowledge …

Escherichia coli synthesize over 60 poorly understood small proteins of less than 50 amino
acids. A striking feature of these proteins is that 65% contain a predicted α-helical …

Membrane proteins must be inserted into a membrane and folded into their correct structure
to function correctly. This insertion occurs during translation and synthesis by the ribosome …