Predictive and prognostic molecular biomarkers for response to neoadjuvant chemoradiation in rectal cancer

D Dayde, I Tanaka, R Jain, MC Tai… - International journal of …, 2017 - mdpi.com
The standard of care in locally advanced rectal cancer is neoadjuvant chemoradiation
(nCRT) followed by radical surgery. Response to nCRT varies among patients and …

Predicting pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a systematic review

JE Ryan, SK Warrier, AC Lynch, RG Ramsay… - Colorectal …, 2016 - Wiley Online Library
Aim Approximately 20% of patients treated with neoadjuvant chemoradiotherapy (nCRT) for
locally advanced rectal cancer achieve a pathological complete response (p CR) while the …

What has preoperative radio (chemo) therapy brought to localized rectal cancer patients in terms of perioperative and long‐term outcomes over the past decades? A …

B Ma, P Gao, H Wang, Q Xu, Y Song… - … journal of cancer, 2017 - Wiley Online Library
We asked what preoperative radiotherapy/chemoradiotherapy (PRT/PCRT) has brought to
patients in terms of perioperative and long‐term outcomes over the past decades. A …

Predictors of pathologic complete response following neoadjuvant chemoradiotherapy for rectal cancer

E Al-Sukhni, K Attwood, DM Mattson, E Gabriel… - Annals of surgical …, 2016 - Springer
Background Some patients with rectal cancer who receive neoadjuvant chemoradiotherapy
(nCRT) achieve a pathologic complete response (pCR) and may be eligible for less radical …

Watch-and-wait as a therapeutic strategy in rectal cancer

L Bernier, S Balyasnikova, D Tait, G Brown - Current colorectal cancer …, 2018 - Springer
Abstract Purpose of Review Pathological complete response is seen in approximately one
fifth of rectal cancer patients following neoadjuvant chemoradiation. Since these patients …

CEA–a predictor for pathologic complete response after neoadjuvant therapy for rectal cancer

U Wallin, D Rothenberger, A Lowry… - Diseases of the colon …, 2013 - journals.lww.com
BACKGROUND: Preoperative chemoradiation therapy in patients with rectal cancer results
in pathologic complete response in approximately 10% to 30% of patients. Accurate …

Predictors and risk factors of pathologic complete response following neoadjuvant chemoradiotherapy for rectal cancer: a population-based analysis

Y Tan, D Fu, D Li, X Kong, K Jiang, L Chen… - Frontiers in …, 2019 - frontiersin.org
Background: Patients with rectal cancer who achieve pathologic complete response (pCR)
after neoadjuvant chemoradiotherapy (nCRT) may have a better prognosis and may be …

Neutrophil–lymphocyte ratio and CEA level as prognostic and predictive factors in colorectal cancer: A systematic review and meta-analysis

PL Tsai, WJ Su, WH Leung, CT Lai… - Journal of cancer …, 2016 - journals.lww.com
Aims: There is a growing body of evidence showing the functional relationship between
inflammation index like netrophil-lymphocyte ratio.(NLR) and colorectal cancer.(CRC) in …

Predictors of complete response and disease recurrence following chemoradiation for rectal cancer

DS Bitterman, L Resende Salgado, HG Moore… - Frontiers in …, 2015 - frontiersin.org
Objective Approximately 10–40% of rectal patients have a complete response (CR) to
neoadjuvant chemoradiation (CRT), and these patients have improved survival. Thus, non …

Clinical parameters predicting pathologic complete response following neoadjuvant chemoradiotherapy for rectal cancer

WG Zeng, JW Liang, Z Wang, XM Zhang, JJ Hu… - Chinese journal of …, 2015 - Springer
Introduction Preoperative chemoradiotherapy (CRT), followed by total mesorectal excision,
has become the standard of care for patients with clinical stages II and III rectal cancer …