Toward single cell traction microscopy within 3D collagen matrices

MS Hall, R Long, X Feng, YL Huang, CY Hui… - Experimental cell …, 2013 - Elsevier
Mechanical interaction between the cell and its extracellular matrix (ECM) regulates cellular
behaviors, including proliferation, differentiation, adhesion, and migration. Cells require the …

Microdeformation in wound healing

C Wiegand, R White - Wound Repair and Regeneration, 2013 - Wiley Online Library
Mechanical forces greatly influence cellular organization and behavior. Cells respond to
applied stress by changes in form and composition until a suitable state is reestablished …

Mechanics of a fiber network within a non-fibrillar matrix: model and comparison with collagen-agarose co-gels

SP Lake, MF Hadi, VK Lai, VH Barocas - Annals of biomedical engineering, 2012 - Springer
While collagen is recognized as the predominant mechanical component of soft connective
tissues, the role of the non-fibrillar matrix (NFM) is less well understood. Even model …

A multiscale approach to modeling the passive mechanical contribution of cells in tissues

VK Lai, MF Hadi, RT Tranquillo… - Journal of …, 2013 - asmedigitalcollection.asme.org
In addition to their obvious biological roles in tissue function, cells often play a significant
mechanical role through a combination of passive and active behaviors. This study focused …

Shear-induced force transmission in a multicomponent, multicell model of the endothelium

M Dabagh, P Jalali, PJ Butler… - Journal of The Royal …, 2014 - royalsocietypublishing.org
Haemodynamic forces applied at the apical surface of vascular endothelial cells (ECs)
provide the mechanical signals at intracellular organelles and through the inter-connected …

An overview of mechanical tests for polymeric biomaterial scaffolds used in tissue engineering

OR Vazquez, IO Avila, JCS Díaz… - Journal of Research …, 2015 - lifescienceglobalca.com
Mechanical characterization of polymeric biomaterial scaffolds is essential to allow
biomaterials that interface with tissues and tissue engineered constructs to be developed …

Multiscale strain analysis of tissue equivalents using a custom-designed biaxial testing device

BJ Bell, E Nauman, SL Voytik-Harbin - Biophysical Journal, 2012 - cell.com
Mechanical signals transferred between a cell and its extracellular matrix play an important
role in regulating fundamental cell behavior. To further define the complex mechanical …

Oligomers modulate interfibril branching and mass transport properties of collagen matrices

CF Whittington, E Brandner, KY Teo… - Microscopy and …, 2013 - academic.oup.com
Mass transport within collagen-based matrices is critical to tissue development, repair, and
pathogenesis, as well as the design of next-generation tissue engineering strategies. This …

Finite element analysis of the effects of focal adhesion mechanical properties and substrate stiffness on cell migration

HC Wong, WC Tang - Journal of biomechanics, 2011 - Elsevier
The attachment of cells to the extracellular matrix (ECM) is achieved by the specific binding
of cell-surface receptors to ligands present in the ECM. These interactions are important for …

Effect of random fiber networks on bubble growth in gelatin hydrogels

F Hasan, KAH Al Mahmud, MI Khan, W Kang, A Adnan - Soft Matter, 2021 - pubs.rsc.org
In hydrodynamics, the event of dynamic bubble growth in a pure liquid under tensile
pressure is known as cavitation. The same event can also be observed in soft materials (eg …