[HTML][HTML] Advances and perspectives in prostate cancer biomarker discovery in the last 5 years through tissue and urine metabolomics

AR Lima, J Pinto, F Amaro, ML Bastos, M Carvalho… - Metabolites, 2021 - mdpi.com
Prostate cancer (PCa) is the second most diagnosed cancer in men worldwide. For its
screening, serum prostate specific antigen (PSA) test has been largely performed over the …

[HTML][HTML] Volatilomics: an emerging and promising avenue for the detection of potential prostate cancer biomarkers

CV Berenguer, F Pereira, JAM Pereira, JS Câmara - Cancers, 2022 - mdpi.com
Simple Summary The lack of highly specific and sensitive biomarkers for the early detection
of prostate cancer (PCa) is a major barrier to its management. Volatilomics emerged as a …

Detection of the prostate cancer biomarker PCA3 with electrochemical and impedance-based biosensors

JC Soares, AC Soares, VC Rodrigues… - … applied materials & …, 2019 - ACS Publications
Diagnosis of prostate cancer via PCA3 biomarker detection is promising to be much more
efficient than with the prostatic specific antigens currently used. In this study, we present the …

[HTML][HTML] Electrochemical and optical detection and machine learning applied to images of genosensors for diagnosis of prostate cancer with the biomarker PCA3

VC Rodrigues, JC Soares, AC Soares, DC Braz… - Talanta, 2021 - Elsevier
The development of simple detection methods aimed at widespread screening and testing is
crucial for many infections and diseases, including prostate cancer where early diagnosis …

Synthesis of new thiazolo-pyrrolidine–(spirooxindole) tethered to 3-acylindole as anticancer agents

MS Islam, HM Ghawas, FF El-Senduny, AM Al-Majid… - Bioorganic …, 2019 - Elsevier
Anticancer therapeutics with profiles of high potency, low toxicity, and low resistance is of
considerable interest. A new series of functionalized spirooxindole linked with 3-acylindole …

[HTML][HTML] Ubiquitin-like modifier activating enzyme 1 as a novel diagnostic and prognostic indicator that correlates with ferroptosis and the malignant phenotypes of liver …

Y Shan, G Yang, H Huang, Y Zhou, X Hu, Q Lu… - Frontiers in …, 2020 - frontiersin.org
Purpose Ferroptosis is a type of cell death that is iron dependent, a characteristic that
distinguishes it from necrosis, apoptosis, and autophagy. However, the ferroptotic …

[HTML][HTML] Seminal exosomes–an important biological marker for various disorders and syndrome in human reproduction

AS Vickram, PS Srikumar, S Srinivasan… - Saudi journal of …, 2021 - Elsevier
Background Exosomes are nano-sized membrane vesicles, secreted by different types of
cells into the body's biological fluids. They are found in abundance in semen as compared to …

Application of urinary volatile organic compounds (VOCs) for the diagnosis of prostate cancer

Q Gao, X Su, MH Annabi, BR Schreiter, T Prince… - Clinical genitourinary …, 2019 - Elsevier
Abstract Background Prostate cancer (PCa) screening using serum prostate-specific antigen
(PSA) testing has caused unnecessary biopsies and overdiagnosis owing to its low …

[HTML][HTML] Gold nanoparticles-MWCNT based aptasensor for early diagnosis of prostate cancer

A Alnaimi, A Al-Hamry, Y Makableh, A Adiraju… - Biosensors, 2022 - mdpi.com
Prostate cancer is one of the most frequently diagnosed male malignancies and can be
detected by prostate-specific antigen (PSA) as a biomarker. To detect PSA, several studies …

[HTML][HTML] Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT.

FC Hamdy, JL Donovan, JA Lane… - Health Technology …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Prostate cancer is the most common cancer among men in the UK. Prostate-
specific antigen testing followed by biopsy leads to overdetection, overtreatment as well as …