Recent developments in super-resolution fluorescence microscopic techniques (SRM) have
allowed for nanoscale imaging that greatly facilitates our understanding of nanostructures …

Single-molecule localization microscopy (SMLM) breaks the optical diffraction limit by
numerically localizing sparse fluorescence emitters to achieve super-resolution imaging …

While critical to biological processes, molecular diffusion is difficult to quantify, and spatial
mapping of local diffusivity is even more challenging. Here we report a machine-learning …

Spectroscopic single-molecule localization microscopy (sSMLM) simultaneously provides
spatial localization and spectral information of individual single-molecules emission, offering …

Recent advancements in deep learning (DL) have propelled the virtual transformation of
microscopy images across optical modalities, enabling unprecedented multimodal imaging …

Single-molecule localization microscopy (SMLM) surpasses the diffraction limit by randomly
switching fluorophores between fluorescent and dark states, precisely pinpointing the …

Super-resolution microscopy can capture spatiotemporal organizations of protein
interactions with resolution down to 10 nm; however, the analyses of more than two proteins …

Optical imaging and single-molecule imaging, in particular, utilize fluorescent tags in order
to differentiate observed species by color. The degree of color multiplexing is dependent on …

Significance The dual-wedge prism (DWP)-based spectroscopic single-molecule
localization microscopy (sSMLM) system offers improved localization precision and …

Spectroscopic single‐molecule localization microscopy (SMLM) has revolutionized the
visualization and analysis of molecular structures and dynamics at the nanoscale level. The …