Expanding drug targets for 112 chronic diseases using a machine learning-assisted genetic priority score
Identifying genetic drivers of chronic diseases is necessary for drug discovery. Here, we
develop a machine learning-assisted genetic priority score, which we call ML-GPS, that …
develop a machine learning-assisted genetic priority score, which we call ML-GPS, that …
Rare variant contribution to the heritability of coronary artery disease
Whole genome sequences (WGS) enable discovery of rare variants which may contribute to
missing heritability of coronary artery disease (CAD). To measure their contribution, we …
missing heritability of coronary artery disease (CAD). To measure their contribution, we …
A digital marker for coronary artery disease
L Koch - Nature Reviews Genetics, 2024 - nature.com
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