It is currently well established that the synthesis of new proteins (mRNA translation) is
required for long-lasting synaptic plasticity and memory formation. Translation in the brain is …

The processing of temporal intervals is essential to create causal maps and to predict future
events so as to best adapt one's behavior. In this review, we explore the different brain …

Adolescents are at increased risk to develop substance use disorders and suffer from
relapse throughout life. Targeted weakening of drug-associated memories has been shown …

Early life experiences can have long-lasting behavioral consequences because they are
encoded when the brain is most malleable. The mechanistic target of rapamycin (mTOR) …

Selective amnesia for previously established memories can be induced by administering
drugs that impair protein synthesis shortly after memory reactivation. Competing theoretical …

Initiated by a long stay of Valérie Doyère in the laboratory of Joseph LeDoux, a Franco–
American collaborative group was formed around the topic of emotion and time perception …

Background Long-term memory formation is generally assumed to involve the permanent
storage of recently acquired memories, making them relatively insensitive to disruption, a …

Early life maltreatment by the caregiver constitutes a major risk factor for the development of
later-life psychopathologies, including fear-related pathologies. Here, we used an animal …

When retrieved under specific circumstances, consolidated fear memories are thought to
return to a labile state, thereby opening a window for modification (eg, attenuation) of the …

Research on retrieval-induced malleability of maladaptive emotional memories has been
mostly focused on the effect of drugs and extinction (ie post-retrieval extinction). Only a few …