Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that affects multiple
organ systems and is caused by loss-of-function mutations in one of two genes: TSC1 or …

Autism spectrum disorder (ASD) represents a heterogeneous group of disorders, which
presents a substantial challenge to diagnosis and treatment. Over the past decade …

There is increasing support for the existence of 'social intelligence'[Humphrey (1984)
Consciousness Regained], independent of general intelligence. Brothers et al.(1990) J …

The long-term consequences of early prefrontal cortex lesions occurring before 16 months
were investigated in two adults. As is the case when such damage occurs in adulthood, the …

Brothers (Brothers L. Concepts in Neuroscience 1990; 1: 27–51) proposed a network of
neural regions that comprise the “social brain”, which includes the amygdala. Since the …

The Child Neurology Society and American Academy of Neurology recently proposed to
formulate Practice Parameters for the Diagnosis and Evaluation of Autism for their …

Although high-functioning individuals with autistic disorder (ie autism and Asperger
syndrome) are of normal intelligence, they have life-long abnormalities in social …

Since autism was first recognized as a disorder in 1943, speculation about its aetiology has
ranged from biological to psychological and back again. After twin studies during the 1970s …

39 interacting with others and may even approach people for attention more often than
children without ADHD. In addition, the intensity the children with ADHD show in their …

Twin and family studies in autistic disorders (AD) have elucidated a high heritability of the
narrow and broad phenotype of AD. In this review on the genetics of AD, we will initially …