Diabetic wound-healing science

JL Burgess, WA Wyant, B Abdo Abujamra, RS Kirsner… - Medicina, 2021 - mdpi.com
Diabetes mellitus is an increasingly prevalent chronic metabolic disease characterized by
prolonged hyperglycemia that leads to long-term health consequences. It is estimated that …

Diabetes and wound angiogenesis

UA Okonkwo, LA DiPietro - International journal of molecular sciences, 2017 - mdpi.com
Diabetes Mellitus Type II (DM2) is a growing international health concern with no end in
sight. Complications of DM2 involve a myriad of comorbidities including the serious …

Consensus guidelines for the use and interpretation of angiogenesis assays

P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov… - Angiogenesis, 2018 - Springer
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

Cell refractive index for cell biology and disease diagnosis: past, present and future

PY Liu, LK Chin, W Ser, HF Chen, CM Hsieh, CH Lee… - Lab on a Chip, 2016 - pubs.rsc.org
Cell refractive index is a key biophysical parameter, which has been extensively studied. It is
correlated with other cell biophysical properties including mechanical, electrical and optical …

Hyperbaric oxygen potentiates diabetic wound healing by promoting fibroblast cell proliferation and endothelial cell angiogenesis

X Huang, P Liang, B Jiang, P Zhang, W Yu, M Duan… - Life sciences, 2020 - Elsevier
Background Diabetic foot ulcer (DFU), one of the diabetic complications, brings high burden
to diabetic patients. Hyperbaric oxygen therapy (HBOT) has been proven to be an effective …

Mechanisms of diabetic foot ulceration: A review

H Deng, B Li, Q Shen, C Zhang, L Kuang… - Journal of …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFUs) are associated with complex pathogenic factors and are
considered a serious complication of diabetes. The potential mechanisms underlying DFUs …

Microneedle arrays for the treatment of chronic wounds

L Barnum, M Samandari, TA Schmidt… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction Chronic wounds are seen frequently in diabetic and bedbound patients. Such
skin injuries, which do not heal in a timely fashion, can lead to life-threatening conditions. In …

High shear stresses under exercise condition destroy circulating tumor cells in a microfluidic system

S Regmi, A Fu, KQ Luo - Scientific reports, 2017 - nature.com
Circulating tumor cells (CTCs) are the primary targets of cancer treatment as they cause
distal metastasis. However, how CTCs response to exercise-induced high shear stress is …

Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes

J Liu, S Yang, B Cao, G Zhou, F Zhang, Y Wang… - Journal of hematology & …, 2021 - Springer
Abstract Background B7-H3, an immune-checkpoint molecule and a transmembrane
protein, is overexpressed in non-small cell lung cancer (NSCLC), making it an attractive …

Flow-induced stress on adherent cells in microfluidic devices

J Shemesh, I Jalilian, A Shi, GH Yeoh, MLK Tate… - Lab on a Chip, 2015 - pubs.rsc.org
Transduction of mechanical forces and chemical signals affect every cell in the human body.
Fluid flow in systems such as the lymphatic or circulatory systems modulates not only cell …