Cerebral small vessel disease: recent advances and future directions

HS Markus, FE de Leeuw - International Journal of Stroke, 2023 - journals.sagepub.com
Cerebral small vessel disease (SVD) causes lacunar stroke and intracerebral hemorrhage,
and is the most common pathology underlying vascular cognitive impairment. Increasingly …

High blood pressure and cardiovascular disease

FD Fuchs, PK Whelton - Hypertension, 2020 - Am Heart Assoc
Fragmented investigation has masked the overall picture for causes of cardiovascular
disease (CVD). Among the risk factors for CVD, high blood pressure (BP) is associated with …

[HTML][HTML] Diretrizes brasileiras de hipertensão arterial–2020

WKS Barroso, CIS Rodrigues, LA Bortolotto… - Arquivos brasileiros de …, 2021 - SciELO Brasil
A hipertensão arterial (HA) é uma doença crônica não transmissível (DCNT) definida por
níveis pressóricos, em que os benefícios do tratamento (não medicamentoso e/ou …

Brazilian guidelines of hypertension–2020

WKS Barroso, CIS Rodrigues, LA Bortolotto… - Arquivos brasileiros de …, 2021 - SciELO Brasil
SciELO - Brasil - Diretrizes Brasileiras de Hipertensão Arterial – 2020 Diretrizes Brasileiras de
Hipertensão Arterial – 2020 Acessibilidade / Reportar erro Brasil Lista alfabética de periódicos …

[HTML][HTML] Vascular cognitive impairment (VCI)

T Rundek, M Tolea, T Ariko, EA Fagerli, CJ Camargo - Neurotherapeutics, 2023 - Elsevier
Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …

Association of blood pressure lowering with incident dementia or cognitive impairment: a systematic review and meta-analysis

D Hughes, C Judge, R Murphy, E Loughlin, M Costello… - Jama, 2020 - jamanetwork.com
Importance The benefit of blood pressure lowering for the prevention of dementia or
cognitive impairment is unclear. Objective To determine the association of blood pressure …

The neurovasculome: key roles in brain health and cognitive impairment: a scientific statement from the American Heart Association/American Stroke Association

C Iadecola, EE Smith, J Anrather, C Gu, A Mishra… - Stroke, 2023 - Am Heart Assoc
Background: Preservation of brain health has emerged as a leading public health priority for
the aging world population. Advances in neurovascular biology have revealed an intricate …

Hypertension, neurovascular dysfunction, and cognitive impairment

MM Santisteban, C Iadecola, D Carnevale - Hypertension, 2023 - Am Heart Assoc
Hypertension affects a significant proportion of the adult and aging population and
represents an important risk factor for vascular cognitive impairment and late-life dementia …

Isosorbide mononitrate and cilostazol treatment in patients with symptomatic cerebral small vessel disease: the lacunar intervention trial-2 (LACI-2) randomized …

JM Wardlaw, LJ Woodhouse, II Mhlanga… - JAMA …, 2023 - jamanetwork.com
Importance Cerebral small vessel disease (cSVD) is a common cause of stroke (lacunar
stroke), is the most common cause of vascular cognitive impairment, and impairs mobility …

Mechanisms of cognitive dysfunction in CKD

D Viggiano, CA Wagner, G Martino… - Nature Reviews …, 2020 - nature.com
Cognitive impairment is an increasingly recognized major cause of chronic disability and is
commonly found in patients with chronic kidney disease (CKD). Knowledge of the …